A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology.
Version 1

Genomic data allow the large-scale manual or semi-automated assembly of metabolic network reconstructions, which provide highly curated organism-specific knowledge bases. Although several genome-scale network reconstructions describe Saccharomyces cerevisiae metabolism, they differ in scope and content, and use different terminologies to describe the same chemical entities. This makes comparisons between them difficult and underscores the desirability of a consolidated metabolic network that collects and formalizes the 'community knowledge' of yeast metabolism. We describe how we have produced a consensus metabolic network reconstruction for S. cerevisiae. In drafting it, we placed special emphasis on referencing molecules to persistent databases or using database-independent forms, such as SMILES or InChI strings, as this permits their chemical structure to be represented unambiguously and in a manner that permits automated reasoning. The reconstruction is readily available via a publicly accessible database and in the Systems Biology Markup Language (http://www.comp-sys-bio.org/yeastnet). It can be maintained as a resource that serves as a common denominator for studying the systems biology of yeast. Similar strategies should benefit communities studying genome-scale metabolic networks of other organisms.

Originating from BioModels: http://www.ebi.ac.uk/biomodels-main/MODEL0072364382

SEEK ID: https://testing.sysmo-db.org/models/40?version=1

1 item is associated with this Model:
  • MODEL0072364382.xml (SBML and XML document - 4.2 MB) Download

Organism: Not specified

Model type: Not specified

Model format: SBML

Execution or visualisation environment: Not specified

Model image: No image specified

This Model was originally imported from the EBI Biomodels: http://www.ebi.ac.uk/biomodels-main/MODEL0072364382.

help Creators and Submitter

Views: 836   Downloads: 60

Created: 7th Sep 2012 at 14:24

help Tags

This item has not yet been tagged.

help Attributions


Version History

Version 1 (earliest) Created 7th Sep 2012 at 14:24 by Stuart Owen

No revision comments

Powered by
Copyright © 2008 - 2024 The University of Manchester and HITS gGmbH