Projects

Test project for uploads from pISA tree

SP1: Understanding and exploiting molecular and cellular reprogramming in response to EZH2 inhibition in PDAC

In SP1, the Hauschild and Hessmann groups will combine their expertise in bioinformatics, machine learning, as well as advanced AI methods and Gl cancer modeling and epigenetic targeting, respectively, to dissect the molecular underpinnings and the therapeutic consequences of EZH2-inhibition (EZH2i)-induced adaptation in PDAC. In the canonical Polycomb-Repressor-Complex 2 pathway, EZH2 ...

The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:

• maximises the ‘shelf life’ and utility of data generated by SysMO;
• provides an integrated platform for the dissemination ...