Glucose metabolism in Plasmodium falciparum trophozoites

The investigation entails the construction and validation of a detailed mathematical model for glycolysis of the malaria parasite Plasmodium falciparum in the blood stage trophozoite form.

DOI: 10.5072/seek.investigation.12.3

Created at: 26th Oct 2017 at 13:35

Contents

Model validation

This study includes the experimental data for model validation and the model predictions of that data set.

GLC incubation

No description specified

5mM GLC runout data.

No description specified

  • Validation-5mMGLCrunout-penkler2.xlsx

Kinetic model for incubation

Glycolytic model for Plasmodium falciparum; closed system

  • penkler2.dat
  • penkler2.nb
  • penkler2.sedx

Validation experiments

SOP for the determination of external metabolites (Glc, Pyr, Gly, Lac) in intact trophozoite incubations, and for the determination of intracellular metabolite concentrations.

  • Validation SOP.docx
Fingerprints

These checksums allow you to check a Snapshot you have downloaded hasn't been modified. For details on how to use these please visit this guide

MD5: 48e3efd1b592298e1837af7e71158d27

SHA1: 851103bb549b0521348066561661fd27a855fdc2

Citation
An error occurred whilst fetching the citation
Snapshots
Snapshot 3 (26th Oct 2017) DOI
Snapshot 2 (22nd Oct 2015) DOI
Snapshot 1 (21st Oct 2015) DOI
Activity

Views: 458   Downloads: 7

Created: 26th Oct 2017 at 13:35

Last updated: 26th Oct 2017 at 13:35

(Since September 2018)

Powered by
(v.1.16.0-pre)
Copyright © 2008 - 2024 The University of Manchester and HITS gGmbH