Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets. Version 1
Targeting persistent tubercule bacilli has become an important challenge in the development of anti-tuberculous drugs. As the glyoxylate bypass is essential for persistent bacilli, interference with it holds the potential for designing new antibacterial drugs. We have developed kinetic models of the tricarboxylic acid cycle and glyoxylate bypass in Escherichia coli and Mycobacterium tuberculosis, and studied the effects of inhibition of various enzymes in the M. tuberculosis model.
SEEK ID: https://testing.sysmo-db.org/models/54?version=1
1 item is associated with this Model:- BIOMD0000000222.xml (SBML and XML document - 49 KB)
Organism: Not specified
Model type: Not specified
Model format: SBML
Execution or visualisation environment: Not specified
Model image: No image specified
This Model was originally imported from the EBI Biomodels: http://www.ebi.ac.uk/biomodels-main/BIOMD0000000222.
Export PNG
Download
Views: 886 Downloads: 1
Created: 29th Nov 2012 at 09:15
TagsThis item has not yet been tagged.
AttributionsNone
Version History
Version 1 (earliest) Created 29th Nov 2012 at 09:15 by Guest
No revision comments
Related items
Projects: Test project 2021-07-18 23:23:02
Institutions: National Institute of Biology
Special guest appearance from Charles Darwin himself!
The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:
- maximises the ‘shelf life’ and utility of data generated by SysMO;
- provides an integrated platform for the dissemination ...
Programme: Dummy programme
Public web page: http://www.sysmo-db.org/
