reports/12864_2015_1880_MOESM1_ESM Top100 Tc RNAi lethal genes annotated.xlsx

Selected Cell

Cell:

Value:

Tabelle1_MPE CPB_orths_blastn CPB_genome_orths_blastn CPB_genome_orths_blastp flybase_lethal Dm_LETHAL_PHENOTYPE biomart_FASTA Tabelle2 Tabelle3 Tabelle4 Tabelle5

100

Top 100 RNAi target genes

Tc Annotation UniProt)

Dm Annotation (Biomart)

CPB_RNAseq data

Symbol

Tc gene

found in biomart

Dm gene

Dm gene name

Entry

Entry name

Protein names

Gene names

Gene names (primary )

Length

Function [CC]

Protein families

Catalytic activity

Gene ontology (biological process)

Gene ontology (molecular function)

Cross-reference (InterPro)

Cross-reference (Pfam)

Cross-reference (PROSITE)

Gene stable ID

Gene name

Gene description

Additional annotation/function (manual)

High gene expression in FlyAtlas (manual inspection)

flybase lethal alleles

lethal_phenotype_stage in Dm

CPB_ORTHOLOG_cDNA (blastN nucl) E<E-10

CPB_ORTHOLOG (blastN nucl genome) E<E-10

CPB_ORTHOLOG (blastP) E<E-10

exon reads in H-reared

exon reads in control-reared

control-reared RPKM

PVY-reared RPKM

healthy-reared RPKM

RPKM logFC(H/C)

RPKM logFC(H/PVY)

PATENTED CPB SEQUENCE (blastn)

candidate?

already described in other literature

iB_00003

TC000029

CG1212

p130CAS

D6WE77

D6WE77_TRICA

Putative uncharacterized protein

TcasGA2_TC000029

765

IPR021901;IPR014928;IPR001452;

PF12026;PF08824;PF14604;

PS50002;

FBgn0035101

p130CAS

p130CAS [Source:FlyBase gene name;Acc:FBgn0035101]

CNS, gut

gb|EB757552.1

LDEC021340

0.5899552009258804

1.1412567340538347

1.5069455686363036

1.352949996584352

0.40100393431982506

iB_00004

TC000040

CG42341

Pka-R1

D6WDE6

D6WDE6_TRICA

Putative uncharacterized protein

TcasGA2_TC000040

372

cAMP-dependent protein kinase regulator activity [GO:0008603]

IPR012198;IPR003117;IPR018490;IPR018488;IPR000595;IPR014710;

PF00027;PF02197;

PS00888;PS00889;PS50042;

FBgn0259243

Pka-R1

cAMP-dependent protein kinase R1 [Source:FlyBase gene name;Acc:FBgn0259243]

CNS

LDEC004542

0.21925538118701302

0.05

0.8400788514811577

1.937912497305508

4.070524748488849

iB_00011

TC000069

CG4097

Prosβ6

D6WD83

D6WD83_TRICA

Putative uncharacterized protein

TcasGA2_TC000069

235

proteolysis involved in cellular protein catabolic process [GO:0051603]

threonine-type endopeptidase activity [GO:0004298]

IPR029055;IPR001353;IPR023333;

PF00227;

PS51476;

FBgn0002284

Prosbeta6

Proteasome beta6 subunit [Source:FlyBase gene name;Acc:FBgn0002284]

early pupal

LDEC003296

0.41318162086505705

0.21798865087605243

0.7915544412873002

0.9379124973055079

1.8604355529571224

iB_00015

TC000082

CG7506

D6WIQ5

D6WIQ5_TRICA

Putative uncharacterized protein

TcasGA2_TC000082

213

IPR009724;

PF06979;

FBgn0035805

CG7506

TMEM70 family; mitochondrial proton-transporting ATP synthase complex assembly

CNS, gut, larva, pupa

LDEC013408

0.5437116816134004

0.05

0.11573532870761793

-2.232012504136804

1.2108293205500256

iB_00029

TC000161

CG6202

Surf4

D6WCQ4

D6WCQ4_TRICA

Putative uncharacterized protein

TcasGA2_TC000161

270

IPR002995;

PF02077;

PS01339;

FBgn0019925

Surf4

Surfeit 4 [Source:FlyBase gene name;Acc:FBgn0019925]

salivary gland, gut, larva

gb|EB760297.1

LDEC016690

102

5.967318757389598

4.230489320708204

6.073205481094741

0.025375338555847355

0.5216336395053638

iB_00031

TC000165

CG40470

D6WCP6

D6WCP6_TRICA

Aminopeptidase-like protein

TcasGA2_TC000165

928

aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]

IPR024571;IPR001930;IPR014782;

PF11838;PF01433;

FBgn0058470

CG40470

metalloprotease, aminopeptidase

LDEC019591

0.05

iB_00053

TC000258

CG4904

Prosα6

D6WBQ6

D6WBQ6_TRICA

Proteasome subunit alpha type (EC 3.4.25.1)

TcasGA2_TC000258

277

FUNCTION: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. {ECO:0000256|RuleBase:RU000551}.

Peptidase T1A family

CATALYTIC ACTIVITY: Cleavage of peptide bonds with very broad specificity. {ECO:0000256|RuleBase:RU000551}.

ubiquitin-dependent protein catabolic process [GO:0006511]

threonine-type endopeptidase activity [GO:0004298]

IPR029055;IPR000426;IPR023332;IPR001353;

PF00227;PF10584;

PS00388;PS51475;

FBgn0250843

Prosalpha6

Proteasome alpha6 subunit [Source:FlyBase gene name;Acc:FBgn0250843]

late larval

LDEC019981

5.87532386959039

4.959577518904848

4.502270641408258

-0.38401559758185433

-0.13956444704287785

iB_00063

TC032227

>TC032227 transcript1

CG5706

FBgn0039175

CG5706

Phe-tRNA synthethase

late larval

LDEC003557

0.6588479957708434

0.09931390837609626

0.6010432572274731

-0.13247683058588985

2.5974011471233287

iB_00141

TC000614

CG18495

Prosα1

D6W9B2

D6W9B2_TRICA

Proteasome subunit alpha type (EC 3.4.25.1)

TcasGA2_TC000614

246

Peptidase T1A family

CATALYTIC ACTIVITY: Cleavage of peptide bonds with very broad specificity. {ECO:0000256|RuleBase:RU000551}.

ubiquitin-dependent protein catabolic process [GO:0006511]

threonine-type endopeptidase activity [GO:0004298]

IPR029055;IPR000426;IPR023332;IPR001353;

PF00227;PF10584;

PS00388;PS51475;

FBgn0263121

Prosalpha1

Proteasome alpha1 subunit [Source:FlyBase gene name;Acc:FBgn0263121]

LDEC010921

0.05

L10

iB_00322

TC002003

CG5848

cact

D7EHY7

D7EHY7_TRICA

Cactus

cact TcasGA2_TC002003

cact

363

IPR002110;IPR020683;

PF12796;

PS50297;PS50088;

FBgn0000250

cact

cactus [Source:FlyBase gene name;Acc:FBgn0000250]

transcription factor

salivary gland

142

LDEC003901

LDEC003916

0.9011914092883527

0.05

0.0959145145391873

-3.232012504136805

0.9398210568442555

L11

iB_00404

TC002574

CG4659

Srp54k

D6WFU9

D6WFU9_TRICA

Putative uncharacterized protein

TcasGA2_TC002574

508

SRP-dependent cotranslational protein targeting to membrane [GO:0006614]

7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]

IPR003593;IPR027417;IPR013822;IPR004125;IPR022941;IPR006325;IPR000897;

PF00448;PF02881;PF02978;

PS00300;

FBgn0010747

Srp54k

Signal recognition particle protein 54k [Source:FlyBase gene name;Acc:FBgn0010747]

salivary gland, embrio

early larval

LDEC007903

3.245844767609468

6.254204597514166

7.02931576590769

1.1147902593895873

0.16855784831945386

yes

L12

iB_00411

TC002601

CG1743

Gs2

D6WFH1

D6WFH1_TRICA

Glutamine synthetase (EC 6.3.1.2)

TcasGA2_TC002601

369

Glutamine synthetase family

CATALYTIC ACTIVITY: ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine. {ECO:0000256|RuleBase:RU004356}.

glutamine biosynthetic process [GO:0006542]

ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]

IPR008147;IPR014746;IPR008146;IPR027303;IPR027302;

PF00120;PF03951;

PS00180;PS00181;

FBgn0001145

Gs2

Glutamine synthetase 2 [Source:FlyBase gene name;Acc:FBgn0001145]

amino acid synthesis

CNS, gut, trachea, larva, adult

LDEC017246

LDEC017247

0.05

L13

iB_00462

TC002881

CG11856

Nup358

D6WHS2

D6WHS2_TRICA

Putative uncharacterized protein

TcasGA2_TC002881

2779

intracellular transport [GO:0046907]

zinc ion binding [GO:0008270]

IPR011993;IPR000156;IPR013026;IPR011990;IPR019734;IPR000697;IPR001876;

PF00638;PF00641;

PS50196;PS50005;PS50293;PS50229;PS01358;PS50199;

FBgn0039302

Nup358

Nucleoporin 358kD [Source:FlyBase gene name;Acc:FBgn0039302]

part of nuclear pore complex

CNS, embrio

early pupal

LDEC004028

0.3184027311016259

0.05

0.20332712717943044

-0.6470500034156483

2.0238027072456672

L14

iB_00472

TC002933

CG8749

snRNP-U1-70K

D6WH33

D6WH33_TRICA

Putative uncharacterized protein

TcasGA2_TC002933

408

nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]

IPR012677;IPR000504;IPR022023;

PF00076;PF12220;

PS50102;

FBgn0016978

snRNP-U1-70K

small ribonucleoprotein particle U1 subunit 70K [Source:FlyBase gene name;Acc:FBgn0016978]

embrio

late pupal

gb|EB754534.1

LDEC020367

7.785803331946993

11.501496436698385

6.463463816497887

-0.2685383801619183

-0.8314421516805459

L15

iB_00503

TC003020

CG14813

δCOP-PB

D6WG69

D6WG69_TRICA

Putative uncharacterized protein

TcasGA2_TC003020

601

protein transport [GO:0015031]

IPR022775;IPR027059;IPR011012;IPR028565;

PF00928;PF01217;

PS51072;

FBgn0028969

deltaCOP

Coat Protein (coatomer) delta [Source:FlyBase gene name;Acc:FBgn0028969]

vesicle transport

salivary gland, gut, embrio, larva

early pupal

gb|EB756576.1

LDEC005928

145

104

11.755986305067223

9.064883117516358

10.466760208824498

-0.16758063154180605

0.20745462880731497

COP beta in CPB (Zhu et al 2011)

L16

iB_00512

TC003079

CG15609

Ehbp1-PG

D6WFM6

D6WFM6_TRICA

Putative uncharacterized protein

TcasGA2_TC003079

948

IPR001715;IPR022735;IPR029944;IPR019448;

PF00307;PF12130;PF10358;

PS50021;

FBgn0034180

Ehbp1

Eps15 homology domain containing protein-binding protein 1 [Source:FlyBase gene name;Acc:FBgn0034180]

LDEC021697

0.49761438686791654

0.2625341577942023

0.4766534352969177

-0.06208750269449213

0.860435552957122

L17

iB_00606

TC003747

CG2063

D6WE90

D6WE90_TRICA

Putative uncharacterized protein

TcasGA2_TC003747

281

regulation of transcription, DNA-templated [GO:0006355]

IPR012479;

PF07818;

FBgn0033400

CG2063

late larval

LDEC012319

0.05

L18

iB_00607

TC003752

CG18412

ph-p

D6WEA2

D6WEA2_TRICA

Polyhomeotic

ph TcasGA2_TC003752

1072

zinc ion binding [GO:0008270]

IPR001660;IPR013761;IPR012313;

PF00536;

PS50105;PS51024;

FBgn0004861

ph-p

polyhomeotic proximal [Source:FlyBase gene name;Acc:FBgn0004861]

Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility. Plays a role in regulating the expression of other pair-rule genes such as eve, ftz, and H

CNS, larva

late pupal

LDEC012135

0.07961830189886665

1.6802186098828946

0.40674426478670317

2.3529499965843517

-2.046455042651396

L19

iB_00621

TC003818

CG9854

hrg

D6WF69

D6WF69_TRICA

Putative uncharacterized protein

TcasGA2_TC003818

565

RNA 3'-end processing [GO:0031123]; RNA polyadenylation [GO:0043631]

polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]

IPR011068;IPR007012;IPR007010;IPR014492;IPR002934;

PF01909;PF04928;PF04926;

FBgn0015949

hrg

hiiragi [Source:FlyBase gene name;Acc:FBgn0015949]

polyA polymerase

CNS, gut

LDEC015830

0.9467168837309845

1.4270689818060036

1.2523007044531527

0.40357606965431964

-0.18847404752382438

L20

iB_00655

TC004029

CG4153

eIF-2β

D6WIW0

D6WIW0_TRICA

Putative uncharacterized protein

TcasGA2_TC004029

312

translation initiation factor activity [GO:0003743]

IPR002735;IPR016189;IPR016190;

PF01873;

FBgn0004926

eIF-2beta

Eukaryotic initiation factor 2beta [Source:FlyBase gene name;Acc:FBgn0004926]

late larval

LDEC017202

9.902059897299564

4.1793469387858595

7.271800065524715

-0.44541614224599757

0.7990350082929789

L21

iB_00731

TC004599

CG7007

VhaPPA1

D6W818

D6W818_TRICA

Putative uncharacterized protein

TcasGA2_TC004599

199

V-ATPase proteolipid subunit family

ATP hydrolysis coupled proton transport [GO:0015991]

hydrogen ion transmembrane transporter activity [GO:0015078]

IPR002379;IPR000245;

PF00137;

FBgn0028662

VhaPPA1-1

Vacuolar H[+] ATPase PPA1 subunit 1 [Source:FlyBase gene name;Acc:FBgn0028662]

late larval

LDEC020050

163

123

44.19940660751447

31.091957400305528

37.40395037002919

-0.24083635452381047

0.2666492018489597

CPB and Diabrotica virgifera (Baum et al 2007)

L22

iB_00753

TC004683

CG8843

Sec5

D6W674

D6W674_TRICA

Putative uncharacterized protein

TcasGA2_TC004683

895

Golgi to plasma membrane transport [GO:0006893]

IPR029175;IPR013783;IPR014756;IPR002909;

PF01833;

FBgn0266670

Sec5

Sec5 ortholog (S. cerevisiae) [Source:FlyBase gene name;Acc:FBgn0266670]

LDEC020746

0.05

0.05127103477997946

0.036215920399625026

L23

iB_00788

TC004949

CG18617

Vha100-2

D6WCX7

D6WCX7_TRICA

V-type proton ATPase subunit a

TcasGA2_TC004949

831

FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.

V-ATPase 116 kDa subunit family

ATP hydrolysis coupled proton transport [GO:0015991]

hydrogen ion transmembrane transporter activity [GO:0015078]

IPR002490;IPR026028;

PF01496;

FBgn0028670

Vha100-2

Vacuolar H[+] ATPase 100kD subunit 2 [Source:FlyBase gene name;Acc:FBgn0028670]

adult/pharate

gb|EB757436.1

LDEC017045

130

6.712686743672775

6.5518055214916755

13.931512918257908

1.0533897147254438

1.0883874996354708

CPB and Diabrotica virgifera (Baum et al 2007)

L24

iB_00825

TC005313

CG5395

nmd

D6WV96

D6WV96_TRICA

Putative uncharacterized protein

TcasGA2_TC005313

368

AAA ATPase family

ATP binding [GO:0005524]

IPR003593;IPR003959;IPR003960;IPR027417;

PF00004;

PS00674;

FBgn0005322

nmd

no mitochondrial derivative [Source:FlyBase gene name;Acc:FBgn0005322]

involved in spermatide development

late pupal

LDEC004927

2.185973159228774

3.2951081196543806

1.2962198922581027

-0.7539652073321604

-1.3460153245103044

L25

iB_00950

TC005869

CG18174

Rpn11

D6WVU4

D6WVU4_TRICA

Putative uncharacterized protein

TcasGA2_TC005869

311

IPR000555;IPR024969;

PF01398;PF13012;

FBgn0028694

Rpn11

Regulatory particle non-ATPase 11 [Source:FlyBase gene name;Acc:FBgn0028694]

proteasome

Malpighian Tubules, gut, CNS, larva

early pupal

LDEC002449

0.9229944272550065

1.7043548147123617

2.2102881072236107

1.2598405921928706

0.3750087257868805

L26

iB_00985

TC006047

CG5269

vib

D6WYS3

D6WYS3_TRICA

Putative uncharacterized protein

TcasGA2_TC006047

298

transport [GO:0006810]

IPR001666;IPR023393;

PF02121;

FBgn0262468

vib

vibrator [Source:FlyBase gene name;Acc:FBgn0262468]

gb|EB756002.1

LDEC001900

0.3721993787955148

0.39273402466774976

0.23768084578491291

-0.6470500034156483

-0.724526947764034

L27

iB_01026

TC006281

CG17332

VhaSFD

D6WVU7

D6WVU7_TRICA

V-type proton ATPase subunit H variant-2

VhaSFD TcasGA2_TC006281

VhaSFD

528

ATP hydrolysis coupled proton transport [GO:0015991]

proton-transporting ATPase activity, rotational mechanism [GO:0046961]

IPR011989;IPR016024;IPR000225;IPR004908;IPR011987;

PF11698;

FBgn0027779

VhaSFD

Vacuolar H[+]-ATPase SFD subunit [Source:FlyBase gene name;Acc:FBgn0027779]

early larval

gb|EB756986.1

LDEC002447

209

146

8.957325709474476

6.279428636171164

8.18823573116156

-0.1295154302147826

0.38291934212972095

CPB and Diabrotica virgifera (Baum et al 2007)

L28

iB_01103

TC006982

D7EJY5

D7EJY5_TRICA

Putative uncharacterized protein

TcasGA2_TC006982

1088

ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]

zinc ion binding [GO:0008270]

IPR029006;IPR007123;IPR006900;IPR006896;IPR012990;IPR002035;IPR006895;

PF00626;PF08033;PF04815;PF04811;PF04810;

LDEC005329

3.6358841250432024

2.4464508995187173

3.2303584565242307

-0.17061195947266114

0.40100393431982484

L29

iB_01207

TC007510

CG9177

eIF5

D2A3J2

D2A3J2_TRICA

Putative uncharacterized protein GLEAN_07510

GLEAN_07510 TcasGA2_TC007510

GLEAN_07510

445

translation initiation factor activity [GO:0003743]

IPR016024;IPR016021;IPR002735;IPR016189;IPR016190;IPR003307;

PF01873;PF02020;

PS51363;

FBgn0030719

eIF5

eIF5 [Source:FlyBase gene name;Acc:FBgn0030719]

late larval

LDEC001384

0.73720649906358

0.3889394930284478

0.47076882498461015

-0.6470500034156481

0.2754730522359661

L30

iB_01233

TC007640

CG7957

MED17

D2A2J0

D2A2J0_TRICA

Putative uncharacterized protein GLEAN_07640

GLEAN_07640 TcasGA2_TC007640

GLEAN_07640

639

RNA polymerase II transcription cofactor activity [GO:0001104]

IPR019313;

PF10156;

FBgn0038578

MED17

Mediator complex subunit 17 [Source:FlyBase gene name;Acc:FBgn0038578]

late pupal

LDEC004601

0.05

0.14174379411424068

0.05

-1.5032855718757736

L31

iB_01271

TC007846

CG8432

Rep

D2A2F3

D2A2F3_TRICA

Putative uncharacterized protein GLEAN_07846

GLEAN_07846 TcasGA2_TC007846

GLEAN_07846

496

intracellular protein transport [GO:0006886]; protein geranylgeranylation [GO:0018344]

IPR023753;IPR018203;IPR001738;

PF00996;

FBgn0026378

Rep

Rab escort protein [Source:FlyBase gene name;Acc:FBgn0026378]

early pupal

LDEC003015

0.05

L32

iB_01280

TC007891

CG4157

Rpn12

D2A2W4

D2A2W4_TRICA

Putative uncharacterized protein GLEAN_07891

GLEAN_07891 TcasGA2_TC007891

GLEAN_07891

265

proteolysis [GO:0006508]

IPR006746;

FBgn0028693

Rpn12

Regulatory particle non-ATPase 12 [Source:FlyBase gene name;Acc:FBgn0028693]

proteasome

Malpighian Tubules, gut, CNS, larva

early pupal

emb|JA828861.1

LDEC002389

1.0613722625621713

0.6719575970744961

1.1296268945728087

0.08991559075055795

0.7494042405683784

YES

L33

iB_01347

TC008407

CG31004

mesh

D2A1L3

D2A1L3_TRICA

Putative uncharacterized protein GLEAN_08407

GLEAN_08407 TcasGA2_TC008407

GLEAN_08407

1428

cell-matrix adhesion [GO:0007160]

IPR005533;IPR014756;IPR002909;IPR003886;IPR000436;IPR001846;

PF03782;PF06119;PF01833;PF00094;

PS50856;PS51220;PS50923;PS51233;

FBgn0051004

mesh

mesh [Source:FlyBase gene name;Acc:FBgn0051004]

barrier function of the midgut epithelium, cell adhesion, subcellular localization,

gut, embrio, larva

gb|EB758508.1

LDEC006484

481

424

62.81858253379834

47.837291975549405

45.50780543421619

-0.4650773742088054

-0.07202170668664398

yes

L34

iB_01385

TC008671

CG10938

Prosα5

D6WT31

D6WT31_TRICA

Proteasome subunit alpha type (EC 3.4.25.1)

TcasGA2_TC008671

242

Peptidase T1A family

CATALYTIC ACTIVITY: Cleavage of peptide bonds with very broad specificity. {ECO:0000256|RuleBase:RU000551}.

ubiquitin-dependent protein catabolic process [GO:0006511]

threonine-type endopeptidase activity [GO:0004298]

IPR029055;IPR000426;IPR023332;IPR001353;

PF00227;PF10584;

PS00388;PS51475;

FBgn0016697

Prosalpha5

Proteasome alpha5 subunit [Source:FlyBase gene name;Acc:FBgn0016697]

late larval

LDEC010714

3.011876552095284

1.4124644746822579

1.2822256154186091

-1.2320125041368044

-0.13956444704287785

L35

iB_01456

TC009010

CG7610

ATPsyn-γ

D6WPW7

D6WPW7_TRICA

ATP synthase subunit gamma

TcasGA2_TC009010

291

ATPase gamma chain family

ATP synthesis coupled proton transport [GO:0015986]

proton-transporting ATPase activity, rotational mechanism [GO:0046961]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]

IPR000131;IPR023632;IPR023633;

PF00231;

PS00153;

FBgn0020235

ATPsyn-gamma

ATP synthase-gamma chain [Source:FlyBase gene name;Acc:FBgn0020235]

early larval

gb|EB759532.1

LDEC004838

0.7639990957289725

1.0300802482709661

1.2739041066962558

0.7376138468196767

0.3064999478565904

L36

iB_01467

TC033679

>TC033679 transcript1

CG18076

shot

FBgn0013733

shot

short stop [Source:FlyBase gene name;Acc:FBgn0013733]

actin-binding

hindgut

105

LDEC009011

2.9292839592590334

1.876615277834243

2.739087077909771

-0.09685292085516871

0.5455622156037102

L37

iB_01493

TC009191

CG1250

Sec23

D6WT99

D6WT99_TRICA

Putative uncharacterized protein

TcasGA2_TC009191

765

ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]

zinc ion binding [GO:0008270]

IPR029006;IPR007123;IPR006900;IPR006896;IPR012990;IPR002035;IPR006895;

PF00626;PF08033;PF04815;PF04811;PF04810;

FBgn0262125

Sec23

Sec23 ortholog (S. cerevisiae) [Source:FlyBase gene name;Acc:FBgn0262125]

late larval

dbj|DM180456.1

LDEC011997

111

3.1518432765472166

5.487460950521157

5.585295331327739

0.8254377680470955

0.025494799227618572

YES

CPB (Zhu et al 2011)

L38

iB_01528

TC009328

CG10540

cpa

D6WRI1

D6WRI1_TRICA

Putative uncharacterized protein

TcasGA2_TC009328

288

barbed-end actin filament capping [GO:0051016]

IPR002189;IPR017865;

PF01267;

PS00748;PS00749;

FBgn0034577

cpa

capping protein alpha [Source:FlyBase gene name;Acc:FBgn0034577]

actin-capping

gut, larva, prepupa

LDEC004416

0.05

L39

iB_01562

TC009491

CG2910

nito

D6WRT8

D6WRT8_TRICA

Putative uncharacterized protein

TcasGA2_TC009491

702

nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]

IPR012677;IPR000504;IPR016194;IPR012921;IPR010912;

PF00076;PF07744;

PS50102;PS50917;

FBgn0027548

nito

spenito [Source:FlyBase gene name;Acc:FBgn0027548]

mRNA splicing

early embrio

late pupal

LDEC019906

0.05

L40

iB_01675

TC010367

CG1088

Vha26

D6WGB5

D6WGB5_TRICA

Putative uncharacterized protein

TcasGA2_TC010367

233

ATP hydrolysis coupled proton transport [GO:0015991]

proton-transporting ATPase activity, rotational mechanism [GO:0046961]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]

IPR002842;

PF01991;

FBgn0015324

Vha26

Vacuolar H[+]-ATPase 26kD subunit [Source:FlyBase gene name;Acc:FBgn0015324]

early pupal

gb|KF833400.1

LDEC013831

156

11.867534674512525

14.856941794329199

20.037873765030355

0.755709166084759

0.43159225415324765

YES

CPB and Diabrotica virgifera (Baum et al 2007)

L41

iB_01682

TC010405

CG3992

srp

D6WKS1

D6WKS1_TRICA

Serpent

srp TcasGA2_TC010405

srp

528

sequence-specific DNA binding [GO:0043565]; transcription factor activity, sequence-specific DNA binding [GO:0003700]; zinc ion binding [GO:0008270]

IPR028436;IPR000679;IPR013088;

PF00320;

PS00344;PS50114;

FBgn0003507

srp

serpent [Source:FlyBase gene name;Acc:FBgn0003507]

transcription factor

fat body, larva

LDEC012258

0.10041790654057539

0.05

0.12825068669245138

0.35294999658435194

1.3589665504728126

L42

iB_01709

TC010557

CG9539

Sec61α

D6WE66

D6WE66_TRICA

Putative uncharacterized protein

TcasGA2_TC010557

476

SecY/SEC61-alpha family

protein transport [GO:0015031]

IPR002208;IPR030659;IPR023201;IPR019561;

PF10559;PF00344;

PS00755;PS00756;

FBgn0086357

Sec61alpha

Sec61 alpha subunit [Source:FlyBase gene name;Acc:FBgn0086357]

protein transporter

gut, fat body, all stages

LDEC003829

295

8.414274778696804

6.975963892776178

16.17451142030301

0.9428112967183468

1.2132576557902681

yes

L43

iB_01800

TC011082

CG2674

Sam-S

D6X4E7

D6X4E7_TRICA

S-adenosylmethionine synthase (EC 2.5.1.6)

TcasGA2_TC011082

439

FUNCTION: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. {ECO:0000256|RuleBase:RU000541}.

AdoMet synthase family

CATALYTIC ACTIVITY: ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine. {ECO:0000256|RuleBase:RU000541}.

one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]

ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]

IPR022631;IPR022630;IPR022629;IPR022628;IPR002133;IPR022636;

PF02773;PF02772;PF00438;

PS00376;PS00377;

FBgn0005278

Sam-S

S-adenosylmethionine Synthetase [Source:FlyBase gene name;Acc:FBgn0005278]

methyl donor

CNS, fat body, hindgut, larva

late pupal

gb|KP689344.1

LDEC003762

LDEC012644

329

498

46.85306360201493

22.23717190227259

19.7661956152447

-1.2451081617484878

-0.1699380960863966

yes

L44

iB_01807

TC011120

CG15811

Rop

D6X469

D6X469_TRICA

Ras opposite

Rop TcasGA2_TC011120

Rop

578

vesicle docking involved in exocytosis [GO:0006904]

IPR027482;IPR001619;

PF00995;

FBgn0004574

Rop

Ras opposite [Source:FlyBase gene name;Acc:FBgn0004574]

vesicle transport, neurotransmitter release

gut, CNS

late pupal

LDEC018675

1.7025329368602222

1.7345165182812647

1.3121518865145552

-0.3757479815982539

-0.4025988528766718

L45

iB_01824

TC011204

CG17420

RpL15

D6X3S2

D6X3S2_TRICA

Ribosomal protein L15

TcasGA2_TC011204

204

Ribosomal protein L15e family

translation [GO:0006412]

structural constituent of ribosome [GO:0003735]

IPR024794;IPR000439;IPR020925;IPR012678;

PF00827;

PS01194;

FBgn0028697

RpL15

Ribosomal protein L15 [Source:FlyBase gene name;Acc:FBgn0028697]

early larval

LDEC005567

0.05

rpl9, rpl19 in CPB and WCR (Baum et al 2007); rpl19 in Bactrocera dorsalis (Chen et al 2015)

L46

iB_01879

TC011708

CG5930

TfIIA-L

D6X0D4

D6X0D4_TRICA

Putative uncharacterized protein

TcasGA2_TC011708

312

transcription initiation from RNA polymerase II promoter [GO:0006367]

IPR009083;IPR004855;IPR013028;IPR009088;

PF03153;

FBgn0011289

TfIIA-L

Transcription factor IIA L [Source:FlyBase gene name;Acc:FBgn0011289]

LDEC010231

1.8312209436739328

0.05

0.5197287827830096

-1.8169750048579605

3.377758958233178

L47

iB_02161

TC013571

CG6625

alpha snap

D6W780

D6W780_TRICA

Putative uncharacterized protein

TcasGA2_TC013571

291

intracellular protein transport [GO:0006886]

IPR000744;IPR011990;

FBgn0250791

alphaSnap

alpha Soluble NSF attachment protein [Source:FlyBase gene name;Acc:FBgn0250791]

ER to Golgi vesicle-mediated transport

CNS, adult

early larval

gb|EB759900.1

LDEC019570

3.1792030272116887

0.5591005212283937

0.676730185915377

-2.232012504136804

0.2754730522359661

L48

iB_03390

TC002507

CG17603

Taf1

D6WH84

D6WH84_TRICA

Putative uncharacterized protein

TcasGA2_TC002507

1887

DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]

DNA binding [GO:0003677]

IPR001487;IPR018359;IPR011177;IPR009067;IPR022591;

PF00439;PF12157;PF09247;

PS00633;PS50014;

FBgn0010355

Taf1

TBP-associated factor 1 [Source:FlyBase gene name;Acc:FBgn0010355]

late pupal

LDEC004538

0.05

L49

iB_00268

TC001600

CG6601

Rab6

D6W6M3

D6W6M3_TRICA

Putative uncharacterized protein

TcasGA2_TC001600

209

Small GTPase superfamily, Rab family

protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]

GTP binding [GO:0005525]

IPR027417;IPR005225;IPR001806;IPR003579;

PF00071;

FBgn0015797

Rab6

Rab6 [Source:FlyBase gene name;Acc:FBgn0015797]

LDEC017315

0.05

rab11 in Bactrocera dorsalis (Li et al 2011)

L50

iB_01793

TC011058

CG18102

shi

D6X4J4

D6X4J4_TRICA

Putative uncharacterized protein

TcasGA2_TC011058

881

TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family

clathrin-mediated endocytosis [GO:0072583]

GTPase activity [GO:0003924]; GTP binding [GO:0005525]

IPR027741;IPR000375;IPR001401;IPR019762;IPR022812;IPR030381;IPR003130;IPR020850;IPR027417;IPR011993;IPR001849;

PF01031;PF00350;PF02212;PF00169;

PS00410;PS51718;PS51388;PS50003;

FBgn0003392

shi

shibire [Source:FlyBase gene name;Acc:FBgn0003392]

dynamin GTPase, actin binding, vesicular trafficing

CNS, eye, gut, larva, adult

early larval

gb|EB754785.1

LDEC016479

3.367715734576448

1.1845054288351882

3.5842864951737314

0.08991559075055795

1.5974011471233285

in WCR (Baum et al 2007, Supplement)

L51

iB_01796

TC011068

CG2467

pot

D6X4H8

D6X4H8_TRICA

Putative uncharacterized protein

TcasGA2_TC011068

915

IPR001507;

PF00100;

FBgn0250871

pot

papillote [Source:FlyBase gene name;Acc:FBgn0250871]

tranchea, pupa

gb|EB760403.1

LDEC013339

0.10817704062346012

0.05

-1.1133943356392002

L52

iB_01857

TC031473

>TC031473 transcript1

CG1782

Uba1

FBgn0023143

Uba1

Ubiquitin activating enzyme 1 [Source:FlyBase gene name;Acc:FBgn0023143]

gb|EB760914.1

LDEC005909

2.4037178603580727

1.7392001812469207

0.964843037344696

-1.3169014017233174

-0.8500578298478931

L53

iB_01884

TC011725

CG6022

Cchl

D6X0A1

D6X0A1_TRICA

Putative uncharacterized protein

TcasGA2_TC011725

256

holocytochrome-c synthase activity [GO:0004408]

IPR000511;

PF01265;

PS00822;

FBgn0038925

Cchl

Cytochrome c heme lyase [Source:FlyBase gene name;Acc:FBgn0038925]

late larval

LDEC007421

3.4458458617520242

1.2985560493046564

4.715281295410369

0.452485670135266

1.8604355529571224

L54

iB_02377

TC015014

CG9012

Chc

D2A6C5

D2A6C5_TRICA

Clathrin heavy chain

GLEAN_15014 Chc TcasGA2_TC015014

GLEAN_15014

1684

FUNCTION: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. {ECO:0000256|PIRNR:PIRNR002290}.

Clathrin heavy chain family

intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]

structural molecule activity [GO:0005198]

IPR016024;IPR000547;IPR016025;IPR012331;IPR015348;IPR001473;IPR022365;IPR016341;IPR011990;

PF00637;PF09268;PF01394;

PS50236;

FBgn0000319

Chc

Clathrin heavy chain [Source:FlyBase gene name;Acc:FBgn0000319]

vesicle transport

gut

early pupal

gb|EB761575.1

LDEC017401

370

219

7.864711850184172

3.8651090943533015

8.48513907410683

0.10954439749949041

1.1344291707807823

yes

L55

iB_02456

TC015321

CG6593

pp1alpha-96a

D2A4R4

D2A4R4_TRICA

Serine/threonine-protein phosphatase (EC 3.1.3.16)

GLEAN_15321 TcasGA2_TC015321

GLEAN_15321

327

PPP phosphatase family

CATALYTIC ACTIVITY: [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate. {ECO:0000256|RuleBase:RU004273, ECO:0000256|SAAS:SAAS00336407}.

phosphoprotein phosphatase activity [GO:0004721]

IPR004843;IPR029052;IPR006186;IPR031675;

PF00149;PF16891;

PS00125;

FBgn0003134

Pp1alpha-96A

Protein phosphatase 1alpha at 96A [Source:FlyBase gene name;Acc:FBgn0003134]

protein phosphorilation

adult crop, fat body, gut

late pupal

gb|EB760859.1

LDEC001822

12.683258514892016

6.797718210608017

8.356457177002545

-0.6019621138871104

0.2978408652644204

L56

iB_02457

TC015322

CG11154

ATPsyn-β

D2A4R3

D2A4R3_TRICA

ATP synthase subunit beta (EC 3.6.3.14)

GLEAN_15322 TcasGA2_TC015322

GLEAN_15322

518

FUNCTION: Produces ATP from ADP in the presence of a proton gradient across the membrane. {ECO:0000256|RuleBase:RU003553}.

ATPase alpha/beta chains family

CATALYTIC ACTIVITY: ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). {ECO:0000256|RuleBase:RU003553}.

ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]

ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]

IPR003593;IPR020003;IPR005722;IPR000793;IPR000194;IPR004100;IPR024034;IPR027417;

PF00006;PF00306;PF02874;

PS00152;

FBgn0010217

ATPsyn-beta

ATP synthase-beta [Source:FlyBase gene name;Acc:FBgn0010217]

gb|EB760184.1

LDEC020740

1083

365

43.95026594167448

54.6336206330281

83.27519144177397

0.9220148704252993

0.6080977302548327

L57

iB_02509

TC015727

CG17170

su(f)

D2A3P0

D2A3P0_TRICA

Putative uncharacterized protein GLEAN_15727

GLEAN_15727 TcasGA2_TC015727

GLEAN_15727

710

mRNA processing [GO:0006397]

IPR003107;IPR008847;IPR011990;

PF05843;

FBgn0003559

su(f)

suppressor of forked [Source:FlyBase gene name;Acc:FBgn0003559]

LDEC005185

0.2923405082493507

0.3084692530915276

0.2800262838270526

-0.06208750269449196

-0.13956444704287801

L58

iB_02531

TC015935

CG13281

Cas

D6WTV7

D6WTV7_TRICA

Putative uncharacterized protein

TcasGA2_TC015935

969

intracellular protein transport [GO:0006886]

IPR011989;IPR016024;IPR005043;IPR013713;IPR001494;

PF03378;PF08506;PF03810;

PS50166;

FBgn0022213

Cas

CAS/CSE1 segregation protein [Source:FlyBase gene name;Acc:FBgn0022213]

zink finger transcription factor

CNS, embrio

late larval

LDEC014614

0.250989712674607

0.7945112670087701

0.16027820192732614

-0.6470500034156483

-2.3094894484851904

some ZnF published in CPB (Liu et al 2014)

L59

iB_02553

TC031972

>TC031972 transcript1

CG5931

l(3)72Ab

FBgn0263599

l(3)72Ab

lethal (3) 72Ab [Source:FlyBase gene name;Acc:FBgn0263599]

LDEC018190

1.1056119293201294

0.6049087571358364

0.6014303333859737

-0.8783755495221037

-0.008319913764625271

L60

iB_02593

TC030579

CG6174

Arp1

D6X502

D6X502_TRICA

Putative uncharacterized protein (Fragment)

TcasGA2_TC030579

360

Actin family

IPR004000;IPR020902;IPR029909;

PF00022;

PS01132;

FBgn0011745

Arp1

Actin-related protein 1 [Source:FlyBase gene name;Acc:FBgn0011745]

LDEC006220

3.280224431814677

1.8058424311825503

2.823293037314246

-0.2164156490857857

0.6447068619016849

L61

iB_02601

TC030625

CG12323

Prosβ5

D6WS19

D6WS19_TRICA

Proteasome subunit beta type (EC 3.4.25.1)

TcasGA2_TC030625

273

Peptidase T1B family

CATALYTIC ACTIVITY: Cleavage of peptide bonds with very broad specificity. {ECO:0000256|RuleBase:RU000694}.

proteolysis involved in cellular protein catabolic process [GO:0051603]

threonine-type endopeptidase activity [GO:0004298]

IPR029055;IPR000243;IPR016050;IPR001353;IPR023333;

PF00227;

PS00854;PS51476;

FBgn0029134

Prosbeta5

Proteasome beta5 subunit [Source:FlyBase gene name;Acc:FBgn0029134]

early pupal

LDEC010014

2.9599476460246756

2.3424383906637876

1.2601182772217365

-1.2320125041368044

-0.8944519492063464

L62

iB_02611

TC030666

CG11522

RpL6

D2A3P5

D2A3P5_TRICA

Putative uncharacterized protein GLEAN_15729-OG20814

GLEAN_15729-OG20814 TcasGA2_TC030666

GLEAN_15729-OG20814

263

translation [GO:0006412]

structural constituent of ribosome [GO:0003735]

IPR000915;IPR014722;IPR005568;IPR008991;

PF01159;PF03868;

FBgn0039857

RpL6

Ribosomal protein L6 [Source:FlyBase gene name;Acc:FBgn0039857]

gb|EB760226.1

LDEC023007

254

153

49.46624371153102

49.46618170868162

52.440854406866166

0.08424684066386579

0.08424864899319713

rpl9, rpl19 in CPB (Baum et al 2007); rpl19 in Bactrocera dorsalis (Chen et al 2015)

L63

iB_02644

TC000801

CG2503

atms

D6WD68

D6WD68_TRICA

Putative uncharacterized protein

TcasGA2_TC000801

465

histone modification [GO:0016570]; transcription elongation from RNA polymerase II promoter [GO:0006368]

IPR007133;

PF03985;

FBgn0010750

atms

antimeros [Source:FlyBase gene name;Acc:FBgn0010750]

transcription cofactor

CNS, embrio

early pupal

LDEC001741

0.7046254730495564

0.10621434704075026

0.9642065973464475

0.45248567013526625

3.1823636478444848

L64

iB_02646

TC030619

CG8118

mam

D6W8H5

D6W8H5_TRICA

Putative uncharacterized protein

TcasGA2_TC030619

805

Notch signaling pathway [GO:0007219]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]

transcription coactivator activity [GO:0003713]

IPR019082;

PF09596;

FBgn0002643

mam

mastermind [Source:FlyBase gene name;Acc:FBgn0002643]

cell division transcription factor

CNS, larva

205

LDEC010363

0.1520947627636157

0.2246803955075964

0.058275237272181306

-1.3840155975818544

-1.9469193691004822

L65

iB_02695

TC003405

D6WG71

D6WG71_TRICA

Putative uncharacterized protein

TcasGA2_TC003405

663

transmembrane transport [GO:0055085]

IPR011701;IPR020846;

PF07690;

PS50850;

FBgn0024315

Picot

Sodium/anion cotransporter

Maybe an inorganic phosphate cotransporter.

gut, CNS, larva, adult gut

LDEC013444

171

16.564683737211304

4.804052891672157

5.072469341063545

-1.7073505136834626

0.07843620517641205

yes

L66

iB_02765

TC008190

CG12202

Nat1

D2A0B9

D2A0B9_TRICA

Putative uncharacterized protein GLEAN_08190

GLEAN_08190 TcasGA2_TC008190

GLEAN_08190

863

IPR021183;IPR013026;IPR011990;IPR013105;IPR019734;

PF12569;PF07719;

PS50005;PS50293;

FBgn0031020

Nat1

NAT1 ortholog (S. cerevisiae) [Source:FlyBase gene name;Acc:FBgn0031020]

N-acetyl transferase

CNS, gut, larva

late pupal

LDEC006073

0.9813617061489458

0.3883141883772767

0.6266826158959119

-0.6470500034156483

0.6905105515148098

!! This is not a solute carrier (CG3252) published in CPB with same gene name (Fu et al 2015)

L67

iB_02771

TC008263

CG10228

inr-a

D2A0S7

D2A0S7_TRICA

Kinesin-like protein

GLEAN_08263 TcasGA2_TC008263

GLEAN_08263

2399

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

microtubule-based movement [GO:0007018]

ATP binding [GO:0005524]; microtubule motor activity [GO:0003777]

IPR006569;IPR008942;IPR027640;IPR019821;IPR001752;IPR027417;IPR006903;

PF04818;PF00225;

PS51391;PS00411;PS50067;

FBgn0264962

Inr-a

Inverse regulator a [Source:FlyBase gene name;Acc:FBgn0264962]

overall low expression

adult/pharate

gb|GO270911.1

LDEC020295

1.1109620362999495

0.8440236173698291

1.021598510129678

-0.12098119174806055

0.2754730522359658

L68

iB_02788

TC013746

D6WJW7

D6WJW7_TRICA

Putative uncharacterized protein

TcasGA2_TC013746

376

Actin family

ATP binding [GO:0005524]

IPR004000;IPR020902;IPR004001;

PF00022;

PS00406;PS00432;PS01132;

gb|KJ577616.1

LDEC008164

0.05

YES

L69

iB_02796

TC014300

CG18398

Tango6

D6WL57

D6WL57_TRICA

Putative uncharacterized protein

TcasGA2_TC014300

900

IPR011989;IPR016024;IPR019451;IPR019414;

PF10363;PF10304;

FBgn0032728

Tango6

Transport and Golgi organization 6 [Source:FlyBase gene name;Acc:FBgn0032728]

LDEC003093

0.07557035918099755

0.05

0.048258078625857195

-0.6470500034156481

-0.051157618457794825

L70

iB_02797

TC031145

>TC031145 transcript1

CG34418

sif

FBgn0085447

sif

still life [Source:FlyBase gene name;Acc:FBgn0085447]

CNS

LDEC012775

0.05

L71

iB_02808

TC033251

>TC033251 transcript1

gb|EB759048.1

LDEC001186

LDEC001072

1.4875170127320747

1.2925993701794058

1.3410433041992793

-0.1495503439448315

0.053080630899517874

L72

iB_02921

TC012455

CG9206

D6X2E3

D6X2E3_TRICA

Putative uncharacterized protein

TcasGA2_TC012455

1206

IPR000938;IPR027663;IPR022157;

PF01302;PF12455;

PS00845;PS50245;

FBgn0001108

Glued [Source:FlyBase gene name;Acc:FBgn0001108]

dynactin 1, vesicle transport

CNS, gut

LDEC017013

L73

iB_03608

TC003731

CG3780

Spx

D6WDW9

D6WDW9_TRICA

Putative uncharacterized protein

TcasGA2_TC003731

393

nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]

IPR012677;IPR000504;

PF00076;

PS50102;

FBgn0015818

Spx

Spliceosomal protein on the X [Source:FlyBase gene name;Acc:FBgn0015818]

late larval

LDEC014838

0.16683864282743557

0.5281299384198238

0.10654061235985528

-0.6470500034156483

-2.30948944848519

L74

iB_03656

TC003944

D6WHZ9

D6WHZ9_TRICA

Putative uncharacterized protein

TcasGA2_TC003944

376

Actin family

ATP binding [GO:0005524]

IPR004000;IPR020902;IPR004001;

PF00022;

PS00406;PS00432;PS01132;

gb|KJ577616.1

LDEC020822

0.05

YES

L75

iB_03752

TC004420

CG1703

D6WD20

D6WD20_TRICA

Putative uncharacterized protein

TcasGA2_TC004420

807

ABC transporter superfamily

ATPase activity [GO:0016887]; ATP binding [GO:0005524]

IPR003593;IPR003439;IPR017871;IPR027417;

PF00005;

PS00211;PS50893;

FBgn0030321

CG1703

ABC transporter

salivary gland

late larval

LDEC001726

3.2468456448119376

0.34259776619952637

1.0366930507639818

-1.6470500034156483

1.5974011471233285

L76

iB_03754

TC004425

CG4147

hsc70-3

D6WD04

D6WD04_TRICA

Putative uncharacterized protein

TcasGA2_TC004425

563

Heat shock protein 70 family

ATP binding [GO:0005524]

IPR018181;IPR029047;IPR013126;

PF00012;

PS00297;PS00329;PS01036;

FBgn0001218

Hsc70-3

Heat shock 70-kDa protein cognate 3 [Source:FlyBase gene name;Acc:FBgn0001218]

gut, fat body, salivary gland, embrio, larva, pupa, adult

late pupal

gb|KC544269.1

LDEC018935

238

8.901768476192728

7.018861928036451

14.86724162287936

0.7399731196935992

1.08282797429357

yes

hsp83 in Aedes aegypti (Sigh et al 2013), hsp70 in B cockerelli (Wuriyanghan et al 2011)

L77

iB_03836

TC004760

CG11152

fd102C

D6W7Y6

D6W7Y6_TRICA

Putative uncharacterized protein

TcasGA2_TC004760

185

IPR006631;

PF07841;

FBgn0039937

fd102C

forkhead domain 102C [Source:FlyBase gene name;Acc:FBgn0039937]

transcription factor

CNS

LDEC008852

0.05

L78

iB_04084

TC006188

CG4644

mtRNApol

D6WV41

D6WV41_TRICA

DNA-directed RNA polymerase (EC 2.7.7.6)

TcasGA2_TC006188

1258

FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. {ECO:0000256|RuleBase:RU003805}.

Phage and mitochondrial RNA polymerase family

CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). {ECO:0000256|RuleBase:RU003805}.

transcription, DNA-templated [GO:0006351]

DNA binding [GO:0003677]; DNA-directed RNA polymerase activity [GO:0003899]

IPR024075;IPR002092;IPR029262;

PF00940;PF14700;

PS00900;PS00489;

FBgn0261938

mtRNApol

mitochondrial RNA polymerase [Source:FlyBase gene name;Acc:FBgn0261938]

LDEC006770

0.6153296181700043

0.05

-3.6213594366451947

RNA Pol II in CPB (Baum et al 2007)

L79

iB_04099

TC006253

CG8566

unc-104

D6WVN9

D6WVN9_TRICA

Kinesin-like protein

TcasGA2_TC006253

1676

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

microtubule-based movement [GO:0007018]

ATP binding [GO:0005524]; microtubule motor activity [GO:0003777]

IPR000253;IPR022164;IPR027640;IPR022140;IPR032405;IPR019821;IPR001752;IPR027417;IPR011993;IPR001849;IPR008984;

PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;

PS00411;PS50067;PS50003;

FBgn0267002

unc-104

unc-104 ortholog (C. elegans) [Source:FlyBase gene name;Acc:FBgn0267002]

myosin-kinesin ATPase, organelle transport

CNS, embrio

LDEC017237

0.059041170482136085

0.06229853628338047

0.22621674514994292

1.937912497305508

1.8604355529571224

L80

iB_04125

TC006375

CG5378

Rpn7

D6WWE7

D6WWE7_TRICA

Putative uncharacterized protein

TcasGA2_TC006375

389

IPR019585;IPR000717;IPR011991;

PF01399;PF10602;

FBgn0028688

Rpn7

Regulatory particle non-ATPase 7 [Source:FlyBase gene name;Acc:FBgn0028688]

proteasome

Malpighian Tubules, gut, CNS, larva

late larval

gb|EB762601.1

LDEC014093

5.86929789639081

3.317739356739919

2.4094569256767273

-1.2844799240309397

-0.46149254193024

L81

iB_04162

TC006514

CG5341

Sec6

D6WXB5

D6WXB5_TRICA

Putative uncharacterized protein

TcasGA2_TC006514

742

exocytosis [GO:0006887]

IPR010326;

PF06046;

FBgn0266671

Sec6

Sec6 ortholog (S. cerevisiae) [Source:FlyBase gene name;Acc:FBgn0266671]

late pupal

gb|EB756972.1

LDEC001544

0.4469008550551378

0.2829341177321352

0.6278449518683857

0.4904535203342868

1.149942170152107

L82

iB_04192

TC006679

CG31992

D6WYF4

D6WYF4_TRICA

Putative uncharacterized protein

TcasGA2_TC006679

1344

nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]

IPR026805;IPR012677;IPR000504;IPR015940;IPR009060;

PF12938;

PS50030;

FBgn0051992

gawky [Source:FlyBase gene name;Acc:FBgn0051992]

involved in miRNA-mediated silencing

CNS, gut

late pupal

LDEC010122

162

4.49681949096102

2.9591936332696736

5.002142514903015

0.1536411883609453

0.7573420599930185

yes

L83

iB_04235

TC006902

D7GYJ9

D7GYJ9_TRICA

Putative uncharacterized protein

TcasGA2_TC006902

186

IPR013026;IPR011990;IPR019734;

PF13414;

PS50005;PS50293;

LDEC010072

0.05

L84

iB_04411

TC007999

CG16916

Rpt3

D2A3L0

D2A3L0_TRICA

Putative uncharacterized protein GLEAN_07999

GLEAN_07999 TcasGA2_TC007999

GLEAN_07999

409

AAA ATPase family

protein catabolic process [GO:0030163]

ATP binding [GO:0005524]; hydrolase activity [GO:0016787]

IPR005937;IPR003593;IPR003959;IPR003960;IPR001270;IPR027417;

PF00004;

PS00674;

FBgn0028686

Rpt3

Regulatory particle triple-A ATPase 3 [Source:FlyBase gene name;Acc:FBgn0028686]

proteasome

Malpighian Tubules, gut, CNS, larva

gb|EB757969.1

LDEC016117

LDEC015181

149

131

19.740778770678507

11.448494148971665

14.338304347268265

-0.46130448449093703

0.32471657125581505

L85

iB_04531

TC008662

CG4584

dUTPase

D6WT48

D6WT48_TRICA

Putative uncharacterized protein

TcasGA2_TC008662

191

dUTP metabolic process [GO:0046080]

dUTP diphosphatase activity [GO:0004170]

IPR029054;IPR008180;IPR008181;

PF00692;

FBgn0250837

dUTPase

Deoxyuridine triphosphatase [Source:FlyBase gene name;Acc:FBgn0250837]

LDEC023112

0.05

L86

iB_04581

TC009040

CG4548

XNP

D6WPQ0

D6WPQ0_TRICA

Putative uncharacterized protein

TcasGA2_TC009040

425

TRNA nucleotidyltransferase/poly(A) polymerase family

RNA processing [GO:0006396]

nucleotidyltransferase activity [GO:0016779]; RNA binding [GO:0003723]

IPR002646;

PF01743;

FBgn0039338

XNP

XNP [Source:FlyBase gene name;Acc:FBgn0039338]

CNS

LDEC015369

0.05

L87

iB_05229

TC012381

CG6843

D6X1Z0

D6X1Z0_TRICA

Putative uncharacterized protein

TcasGA2_TC012381

361

nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]

IPR019339;IPR001878;

PF10197;

FBgn0036827

CG6843

LDEC021145

1.9332991381692703

2.039961361238734

2.0987780765889057

0.11848474294732876

0.04100779859894283

L88

iB_05303

TC012723

CG12104

D6WZT7

D6WZT7_TRICA

Putative uncharacterized protein

TcasGA2_TC012723

534

IPR009071;

PF00505;

PS50118;

FBgn0035238

CG12104

fat body, CNS

LDEC010834

1.630360526775225

0.34406185921747306

3.123370088840202

0.9379124973055081

3.1823636478444848

L89

iB_05370

TC013003

CG5971

Cdc6

D6WJU9

D6WJU9_TRICA

Putative uncharacterized protein

TcasGA2_TC013003

525

cell division [GO:0051301]; DNA replication initiation [GO:0006270]

ATP binding [GO:0005524]

IPR003593;IPR016314;IPR015163;IPR027417;IPR011991;

PF13401;PF09079;

FBgn0035918

Cdc6

Cdc6 [Source:FlyBase gene name;Acc:FBgn0035918]

embrio

LDEC007222

0.46906274171975737

0.05

0.3744203897482619

-0.32512190852828576

2.9046590016620537

L90

iB_05404

TC013245

CG10002

fkh

D6WMG3

D6WMG3_TRICA

Fork head

fkh TcasGA2_TC013245

fkh

431

sequence-specific DNA binding [GO:0043565]; transcription factor activity, sequence-specific DNA binding [GO:0003700]

IPR013638;IPR001766;IPR018533;IPR018122;IPR011991;

PF00250;PF08430;PF09354;

PS00657;PS50039;

FBgn0000659

fkh

fork head [Source:FlyBase gene name;Acc:FBgn0000659]

transcription factor

Malpighian Tubules, salivary gland

LDEC012456

0.05

L91

iB_05526

TC013939

CG1109

D6WNM4

D6WNM4_TRICA

Putative uncharacterized protein

TcasGA2_TC013939

805

IPR015943;IPR001680;IPR017986;

PF00400;

PS50082;PS50294;

FBgn0046222

CG1109

LDEC008911

1.4274550785876983

0.7531046664564199

0.8464402503565162

-0.7539652073321602

0.16855784831945386

L92

iB_05560

TC014109

CG31155

Rpb7

D6WKA0

D6WKA0_TRICA

Putative uncharacterized protein

TcasGA2_TC014109

173

transcription, DNA-templated [GO:0006351]

DNA-directed RNA polymerase activity [GO:0003899]; nucleic acid binding [GO:0003676]

IPR012340;IPR005576;IPR003029;

PF00575;PF03876;

FBgn0051155

Rpb7

Rpb7 [Source:FlyBase gene name;Acc:FBgn0051155]

early pupal

LDEC016281

0.8175093498544342

0.28753741091745966

0.17401633352109697

-2.232012504136804

-0.724526947764034

L93

iB_05604

TC014294

CG1828

dre4

D6WL41

D6WL41_TRICA

Putative uncharacterized protein

TcasGA2_TC014294

1112

IPR029149;IPR013719;IPR029148;IPR013953;IPR000994;

PF14826;PF00557;PF08512;PF08644;

FBgn0002183

dre4

dre4 [Source:FlyBase gene name;Acc:FBgn0002183]

mRNA elongation, DNA repair

CNS, embrio

adult/pharate

gb|EB758030.1

LDEC008327

0.05

L94

iB_05628

TC014413

CG7269

Hel25E

D6WLU7

D6WLU7_TRICA

Putative uncharacterized protein

TcasGA2_TC014413

425

ATP binding [GO:0005524]; helicase activity [GO:0004386]; nucleic acid binding [GO:0003676]

IPR011545;IPR014001;IPR001650;IPR027417;IPR014014;

PF00270;PF00271;

PS51192;PS51194;PS51195;

FBgn0014189

Hel25E

Helicase at 25E [Source:FlyBase gene name;Acc:FBgn0014189]

CNS, salivary gland

early larval

dbj|DM180455.1

LDEC012710

0.05

YES

L95

iB_05683

TC014730

CG12245

gcm

D6WJ63

D6WJ63_TRICA

Putative uncharacterized protein

TcasGA2_TC014730

507

regulation of transcription, DNA-templated [GO:0006355]

DNA binding [GO:0003677]

IPR003902;

PF03615;

PS50807;

FBgn0014179

gcm

glial cells missing [Source:FlyBase gene name;Acc:FBgn0014179]

CNS, embrio

LDEC012509

0.05

L96

iB_05693

TC014785

CG12750

ncm

D6WJQ7

D6WJQ7_TRICA

Putative uncharacterized protein

TcasGA2_TC014785

756

RNA binding [GO:0003723]

IPR016024;IPR003891;IPR016021;IPR003890;

PF02847;PF02854;

PS51366;

FBgn0086707

ncm

nucampholin [Source:FlyBase gene name;Acc:FBgn0086707]

mRNA splicing

salivary gland, embrio

early larval

LDEC005485

0.26616583483632744

0.561700988768991

0.16996944204386213

-0.6470500034156483

-1.7245269477640344

L97

iB_05726

TC014931

CG2909

D2A3W8

D2A3W8_TRICA

Putative uncharacterized protein GLEAN_14931

GLEAN_14931 TcasGA2_TC014931

GLEAN_14931

484

IPR032063;

PF16062;

FBgn0030189

CG2909

Malpighian Tubules, gut

late pupal

LDEC005233

0.15508307449813116

0.4909175308346872

0.05

-1.63304124169283

-3.295480686762372

L98

iB_05983

TC016270

CG3962

Keap1

D6X2W3

D6X2W3_TRICA

Putative uncharacterized protein

TcasGA2_TC016270

606

IPR011705;IPR017096;IPR000210;IPR015915;IPR006652;IPR030605;IPR011333;

PF07707;PF00651;PF01344;

PS50097;

FBgn0038475

Keap1

Keap1 [Source:FlyBase gene name;Acc:FBgn0038475]

protein ubiquitination

LDEC000567

0.9407762361540882

0.8065524087384175

1.839843896154213

0.9676598406995602

1.1897431782100822

↑ Previous 1 2 Next ↓

Query_ID	Query_length	Target_ID	Target_length	Target_description	E-value	Identity%	Aligned_seq_length	Score	Positives%	Gaps%
TC002933	1227	gb\|EB754534.1	547	602231 MN12 Leptinotarsa decemlineata cDNA clone 319105, mRNA sequence	8.0E-42	72	308	168		0
TC003944	1131	gb\|KJ577616.1	1312	Leptinotarsa decemlineata strain Freeville actin mRNA, complete cds	0	82	1131	1133		0
TC004425	1692	gb\|KC544269.1	2397	Leptinotarsa decemlineata heat shock protein 70b mRNA, complete cds	0	79	1579	1379		0
TC003020	1806	gb\|EB756576.1	453	601947 MN12 Leptinotarsa decemlineata cDNA clone 318583, mRNA sequence	2.0E-84	78	382	311		0
TC000161	813	gb\|EB760297.1	442	672744 MN12 Leptinotarsa decemlineata cDNA clone 326766, mRNA sequence	3.0E-45	79	204	179		0
TC000029	2298	gb\|EB757552.1	397	601201 MN12 Leptinotarsa decemlineata cDNA clone 316992, mRNA sequence	4.0E-36	77	207	150		4
TC007891	798	emb\|JA828861.1	906	Sequence 389 from Patent WO2013010691	6.0E-136	74	803	480		1
TC004949	2496	gb\|EB757436.1	481	581736 MN12 Leptinotarsa decemlineata cDNA clone 315587, mRNA sequence	1.0E-50	72	400	199		2
TC011058	2646	gb\|EB754785.1	476	665319 MN12 Leptinotarsa decemlineata cDNA clone 321919, mRNA sequence	1.0E-107	78	475	389		0
TC006375	1170	gb\|EB762601.1	533	677962 MN12 Leptinotarsa decemlineata cDNA clone 327361, mRNA sequence	7.0E-81	75	467	298		1
TC009010	876	gb\|EB759532.1	467	581563 MN12 Leptinotarsa decemlineata cDNA clone 315554, mRNA sequence	1.0E-51	72	380	201		1
TC011082	1320	gb\|KP689344.1	1378	Leptinotarsa decemlineata S-adenosylmethionine synthase mRNA, complete cds	2.0E-120	71	890	430		1
TC008263	7200	gb\|GO270911.1	584	N4(1)B6 Suppressive subtractive hybridization screening of prediapausing Leptinotarsa decemlineata Leptinotarsa decemlineata cDNA, mRNA sequence	2.0E-51	74	325	203		0
TC006281	1587	gb\|EB756986.1	577	667075 MN12 Leptinotarsa decemlineata cDNA clone 323581, mRNA sequence	1.0E-79	74	476	295		0
TC008407	4287	gb\|EB758508.1	455	581616 MN12 Leptinotarsa decemlineata cDNA clone 315629, mRNA sequence	5.0E-51	70	455	201		3
TC006047	897	gb\|EB756002.1	513	667547 MN12 Leptinotarsa decemlineata cDNA clone 323817, mRNA sequence	4.0E-82	79	369	302		1
TC010367	702	gb\|KF833400.1	1041	Leptinotarsa decemlineata vacuolar H[+]-ATPase E subunit mRNA, complete cds	1.0E-99	71	706	360		4
TC009191	2298	dbj\|DM180456.1	1601	TRANSGENIC PLANT-BASED METHODS FOR PLANT PESTS USING RNAi	0	75	1599	1092		2
TC007999	1230	gb\|EB757969.1	493	665630 MN12 Leptinotarsa decemlineata cDNA clone 322431, mRNA sequence	5.0E-89	75	473	325		0
TC006514	2229	gb\|EB756972.1	501	666930 MN12 Leptinotarsa decemlineata cDNA clone 323090, mRNA sequence	5.0E-22	69	267	104		0
TC011068	2748	gb\|EB760403.1	622	677503 MN12 Leptinotarsa decemlineata cDNA clone 325931, mRNA sequence	1.0E-63	78	302	242		0
TC015322	1557	gb\|EB760184.1	452	666943 MN12 Leptinotarsa decemlineata cDNA clone 323419, mRNA sequence	2.0E-75	74	435	280		0
TC015014	5055	gb\|EB761575.1	591	678753 MN12 Leptinotarsa decemlineata cDNA clone 328119, mRNA sequence	2.0E-138	79	585	491		0
TC014413	1278	dbj\|DM180455.1	1031	TRANSGENIC PLANT-BASED METHODS FOR PLANT PESTS USING RNAi	0	78	1029	823		0
TC014294	3339	gb\|EB758030.1	507	666581 MN12 Leptinotarsa decemlineata cDNA clone 322362, mRNA sequence	3.0E-65	79	287	248		0
TC013746	1131	gb\|KJ577616.1	1312	Leptinotarsa decemlineata strain Freeville actin mRNA, complete cds	3.0E-141	70	1131	499		0
TC030666	792	gb\|EB760226.1	592	667515 MN12 Leptinotarsa decemlineata cDNA clone 324003, mRNA sequence	1.0E-30	66	501	131		2
TC015321	984	gb\|EB760859.1	528	614623 MN12 Leptinotarsa decemlineata cDNA clone 318850, mRNA sequence	2.0E-80	77	384	297		0
TC013571	876	gb\|EB759900.1	495	659973 MN12 Leptinotarsa decemlineata cDNA clone 319570, mRNA sequence	6.0E-99	77	460	358		0
TC031473	3126	gb\|EB760914.1	489	622799 MN12 Leptinotarsa decemlineata cDNA clone 319267, mRNA sequence	1.0E-83	74	492	309		2
TC033251	1605	gb\|EB759048.1	412	666013 MN12 Leptinotarsa decemlineata cDNA clone 325507, mRNA sequence	3.0E-29	75	200	127		1

100

Query_ID	Query_length	Target_ID	Target_length	Target_description	E-value	Identity%	Aligned_seq_length	Score	Positives%	Gaps%
TC002601	1110	LDEC017246-RA	466		4.0E-67	80	286	255		0
TC004420	2424	LDEC001726-RA	705		2.0E-131	75	691	470		1
TC002933	1227	LDEC020367-RA	588		6.0E-116	76	566	417		0
TC003405	1992	LDEC013444-RA	2363		0	74	1137	686		0
TC000165	2787	LDEC019591-RA	4097		0	72	1274	663		1
TC000040	1119	LDEC004542-RA	1044		2.0E-152	79	613	538		0
TC004683	2688	LDEC020746-RA	2851		3.0E-142	65	2662	506		2
TC003818	1698	LDEC015830-RA	3385		4.0E-177	71	1290	621		1
TC003752	3219	LDEC012135-RA	2875		1.0E-72	73	471	275		2
TC003944	1131	LDEC020822-RA	1131		0	82	1131	1124		0
TC004425	1692	LDEC018935-RA	2340		0	79	1579	1361		0
TC001600	630	LDEC017315-RA	630		2.0E-155	79	626	547		0
TC002574	1527	LDEC007903-RA	1622		0	80	1527	1386		0
TC004029	939	LDEC017202-RA	1387		9.0E-150	73	962	529		3
TC003020	1806	LDEC005928-RA	2025		3.0E-160	71	1158	565		4
TC003731	1182	LDEC014838-RA	1372		4.0E-86	75	478	318		3
TC002003	1092	LDEC003901-RA	386		2.0E-20	76	143	100		0
TC000082	642	LDEC013408-RA	1263		6.0E-62	71	469	237		3
TC002507	5664	LDEC004538-RA	4296		0	71	2008	991		2
TC000161	813	LDEC016690-RA	2455		9.0E-175	77	812	612		0
TC000029	2298	LDEC021340-RA	2328		6.0E-81	68	907	302		1
TC000614	741	LDEC010921-RA	441		6.0E-69	74	404	260		0
TC004760	558
TC003079	2847	LDEC021697-RA	920		3.0E-66	78	320	253		0
TC000801	1398	LDEC001741-RA	2274		0	77	1047	778		0
TC000258	834	LDEC019981-RA	974		1.0E-116	73	737	419		0
TC002881	8340	LDEC004028-RA	7908		3.0E-161	65	2914	571		2
TC000069	708	LDEC003296-RA	1108		3.0E-104	73	641	378		1
TC004599	600
TC003747	846	LDEC012319-RA	378		7.0E-24	69	326	111		3
TC007891	798	LDEC002389-RA	3235		8.0E-137	74	803	486		1
TC006902	561	LDEC010072-RA	978		5.0E-68	74	392	257		0
TC007846	1491	LDEC003015-RA	1560		4.0E-75	66	1180	282		6
TC004949	2496	LDEC017045-RA	1364		3.0E-174	72	1156	612		1
TC010405	1587	LDEC012258-RA	4559		3.0E-77	70	705	289		7
TC011058	2646	LDEC016479-RA	2243		0	74	1490	987		3
TC009040	1278	LDEC015369-RA	714		3.0E-82	73	537	306		0
TC006375	1170	LDEC014093-RA	1092		5.0E-173	76	828	607		0
TC010557	1431	LDEC003829-RA	2666		0	79	1431	1205		0
TC009010	876	LDEC004838-RA	5393		8.0E-157	75	830	553		0
TC006982	3267	LDEC005329-RA	4344		0	76	1247	888		0
TC011082	1320	LDEC003762-RA	1095		3.0E-120	71	892	432		1
TC005869	936	LDEC002449-RA	992		7.0E-88	75	464	324		0
TC008263	7200	LDEC020295-RA	5151		5.0E-62	76	326	241		0
TC006281	1587	LDEC002447-RA	3731		0	75	1508	1005		1
TC007640	1920	LDEC004601-RA	1704		1.0E-165	71	1206	583		1
TC009491	2109	LDEC019906-RA	1716		0	72	1249	648		4
TC006253	5031	LDEC017237-RA	3877		0	73	1150	666		2
TC008407	4287	LDEC006484-RA	1545		0	71	1442	702		1
TC008190	2592	LDEC006073-RA	1866		0	74	1284	832		2
TC008671	729	LDEC010714-RA	684		6.0E-138	83	479	489		0
TC008662	576
TC006047	897	LDEC001900-RA	615		1.0E-39	72	309	163		1
TC010367	702	LDEC013831-RA	1138		6.0E-100	72	706	363		4
TC009191	2298	LDEC011997-RA	2905		0	76	2331	1671		2
TC006679	4035	LDEC010122-RA	4734		0	71	3131	1409		4
TC007999	1230	LDEC016117-RA	657		8.0E-89	78	399	327		0
TC005313	1107	LDEC004927-RA	1466		2.0E-146	73	922	518		1
TC006514	2229	LDEC001544-RA	2561		1.0E-82	66	969	307		5
TC007510	1338	LDEC001384-RA	621		4.0E-99	74	546	361		4
TC011068	2748	LDEC013339-RA	4232		2.0E-120	65	1894	434		8
TC009328	867	LDEC004416-RA	729		5.0E-121	74	699	434		1
TC006188	3777	LDEC006770-RA	744		3.0E-30	64	651	134		8
TC015322	1557	LDEC020740-RA	1901		0	77	1548	1193		0
TC011725	771	LDEC007421-RA	930		4.0E-64	72	458	244		0
TC014785	2271	LDEC005485-RA	2580		0	73	1710	993		2
TC014109	522	LDEC016281-RA	840		1.0E-125	79	518	448		0
TC015727	2133	LDEC005185-RA	1566		0	75	1184	801		0
TC015014	5055	LDEC017401-RA	6374		0	76	5061	3743		1
TC014300	2703	LDEC003093-RA	3029		1.0E-83	69	747	311		1
TC013939	2418	LDEC008911-RA	2245		0	76	1261	879		1
TC014413	1278	LDEC012710-RA	1278		0	75	1276	854		0
TC014931	1455
TC015935	2910	LDEC014614-RA	912		7.0E-132	73	795	471		0
TC014730	1524	LDEC012509-RA	1647		8.0E-147	71	1143	520		3
TC030619	2418	LDEC010363-RA	7525		3.0E-65	76	356	250		4
TC012455	3621	LDEC017013-RA	2224		1.0E-72	68	828	275		1
TC011204	615	LDEC005567-RA	531		1.0E-69	74	420	262		0
TC011120	1737	LDEC018675-RA	3899		0	77	1182	890		0
TC014294	3339	LDEC008327-RA	3078		0	73	1748	980		1
TC013746	1131	LDEC008164-RA	1131		2.0E-159	71	1131	562		0
TC016270	1821	LDEC000567-RA	3893		0	70	1646	783		3
TC013245	1296	LDEC012456-RA	1284		0	73	1272	744		5
TC013003	1578	LDEC007222-RA	1952		4.0E-87	69	850	322		2
TC012723	1605	LDEC010834-RA	702		3.0E-108	72	686	392		7
TC011708	939	LDEC010231-RA	1125		2.0E-37	69	340	156		10
TC030579	1083	LDEC006220-RA	1605		8.0E-158	72	1077	556		0
TC030625	822	LDEC010014-RA	928		7.0E-151	79	633	533		1
TC030666	792	LDEC023007-RA	708		1.0E-45	68	565	183		2
TC015321	984	LDEC001822-RA	1137		0	80	984	901		0
TC013571	876	LDEC019570-RA	432		2.0E-56	77	279	219		0
TC012381	1086	LDEC021145-RA	1184		2.0E-108	73	683	392		0
TC030708	2448	LDEC018094-RA	2528		4.0E-121	71	831	435		7
TC032227	1788	LDEC003557-RA	2432		2.0E-141	67	1784	502		1
TC033679	654	LDEC009011-RA	2188		1.0E-45	75	266	183		0
TC031473	3126	LDEC005909-RA	3333		0	74	2765	1788		0
TC031972	6414	LDEC018190-RA	5590		0	76	5107	3589		1
TC031145	3522	LDEC012775-RA	1229		0	77	1216	915		0
TC033251	1605	LDEC001186-RA	1155		4.0E-157	72	1099	554		2

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Query_ID	Query_length	Target_ID	Target_length	Target_description	E-value	Identity%	Aligned_seq_length	Score	Positives%	Gaps%
TC002601	369	LDEC017247-PA	107	unnamed protein product	3.0E-62	86	104	197	91	0
TC004420	807	LDEC001726-PA	234	unnamed protein product	3.0E-136	89	226	406	95	0
TC002933	408	LDEC020367-PA	195	unnamed protein product	6.0E-92	95	184	278	98	0
TC003405	663	LDEC013444-PA	503	unnamed protein product	0	75	518	770	86	4
TC000165	928	LDEC019591-PA	891	unnamed protein product	0	68	927	1264	79	6
TC000040	372	LDEC004542-PA	347	unnamed protein product	4.0E-141	96	204	408	98	0
TC004683	895	LDEC020746-PA	877	unnamed protein product	0	68	883	1210	82	1
TC003818	565	LDEC015830-PA	598	unnamed protein product	0	76	552	858	88	1
TC003752	1072	LDEC012135-PA	519	unnamed protein product	6.0E-140	62	436	434	72	9
TC003944	376	LDEC020822-PA	376	unnamed protein product	0	99	376	779	99	0
TC004425	563	LDEC018935-PA	657	unnamed protein product	0	96	526	982	99	0
TC001600	209	LDEC017315-PA	209	unnamed protein product	1.0E-155	99	209	433	100	0
TC002574	508	LDEC007903-PA	508	unnamed protein product	0	95	485	924	98	0
TC004029	312	LDEC017202-PA	331	unnamed protein product	7.0E-153	80	318	435	89	2
TC003020	601	LDEC005928-PA	460	unnamed protein product	0	73	512	754	83	10
TC003731	393	LDEC014838-PA	373	unnamed protein product	4.0E-137	89	213	400	90	10
TC000082	213	LDEC013408-PA	228	unnamed protein product	2.0E-87	62	214	260	75	2
TC002003	363	LDEC003916-PA	336	unnamed protein product	1.0E-78	46	303	247	60	7
TC000029	765	LDEC021340-PA	566	unnamed protein product	5.0E-160	77	311	479	88	1
TC000161	270	LDEC016690-PA	288	unnamed protein product	7.0E-162	93	270	454	98	0
TC002507	1887	LDEC004538-PA	1431	unnamed protein product	0	60	1457	1509	72	9
TC000614	246	LDEC010921-PA	146	unnamed protein product	8.0E-91	93	135	267	98	0
TC004760	185	LDEC008852-PA	194	unnamed protein product	7.0E-37	47	138	128	68	2
TC003079	948	LDEC021697-PA	238	unnamed protein product	5.0E-77	76	184	253	83	7
TC000258	277	LDEC019981-PA	293	unnamed protein product	1.0E-143	82	281	409	89	2
TC000801	465	LDEC001741-PA	723	unnamed protein product	0	92	334	647	96	0
TC000069	235	LDEC003296-PA	246	unnamed protein product	1.0E-145	85	224	410	92	0
TC002881	2779	LDEC004028-PA	2575	unnamed protein product	0	64	968	1294	82	1
TC004599	199	LDEC020050-PA	159	unnamed protein product	5.0E-61	77	158	190	87	4
TC003747	281	LDEC012319-PA	125	unnamed protein product	3.0E-35	73	110	125	80	3
TC007891	265	LDEC002389-PA	266	unnamed protein product	7.0E-150	86	266	423	93	0
TC006902	186	LDEC010072-PA	325	unnamed protein product	2.0E-76	82	156	234	87	7
TC007846	496	LDEC003015-PA	519	unnamed protein product	0	62	519	629	76	7
TC004949	831	LDEC017045-PA	423	unnamed protein product	0	78	425	698	88	2
TC010405	528	LDEC012258-PA	277	unnamed protein product	1.0E-77	63	243	248	77	5
TC011058	881	LDEC016479-PA	595	unnamed protein product	0	87	639	1142	91	7
TC009040	425	LDEC015369-PA	237	unnamed protein product	1.0E-114	75	224	338	83	1
TC006375	389	LDEC014093-PA	363	unnamed protein product	0	85	363	635	90	6
TC010557	476	LDEC003829-PA	476	unnamed protein product	0	99	476	955	99	0
TC009010	291	LDEC004838-PA	296	unnamed protein product	0	84	292	507	90	1
TC006982	1088	LDEC005329-PA	1257	unnamed protein product	0	74	777	1186	83	7
TC011082	439	LDEC012644-PA	406	unnamed protein product	0	78	439	670	86	8
TC005869	311	LDEC002449-PA	268	unnamed protein product	2.0E-174	82	297	487	84	14
TC008263	2399	LDEC020295-PA	1493	unnamed protein product	0	44	1171	762	57	18
TC006281	528	LDEC002447-PA	527	unnamed protein product	0	89	513	943	92	1
TC007640	639	LDEC004601-PA	491	unnamed protein product	0	86	406	706	92	0
TC009491	702	LDEC019906-PA	571	unnamed protein product	0	84	419	637	89	4
TC006253	1676	LDEC017237-PA	395	unnamed protein product	0	86	388	619	91	1
TC008407	1428	LDEC006484-PA	514	unnamed protein product	0	76	503	815	87	0
TC008190	863	LDEC006073-PA	621	unnamed protein product	0	86	433	743	93	2
TC008671	242	LDEC010714-PA	227	unnamed protein product	3.0E-118	94	172	340	95	0
TC008662	191	LDEC023112-PA	233	unnamed protein product	1.0E-13	36	108	66.2	54	16
TC006047	298	LDEC001900-PA	204	unnamed protein product	7.0E-65	55	185	205	65	20
TC010367	233	LDEC013831-PA	231	unnamed protein product	1.0E-94	79	233	280	89	3
TC009191	765	LDEC011997-PA	778	unnamed protein product	0	93	776	1519	96	1
TC006679	1344	LDEC010122-PA	1291	unnamed protein product	0	71	1100	1130	79	3
TC007999	409	LDEC015181-PA	438	unnamed protein product	1.0E-126	52	361	376	77	1
TC005313	368	LDEC004927-PA	374	unnamed protein product	0	76	374	573	88	2
TC006514	742	LDEC001544-PA	733	unnamed protein product	0	67	756	972	80	6
TC007510	445	LDEC001384-PA	206	unnamed protein product	1.0E-114	82	199	338	90	6
TC011068	915	LDEC013339-PA	939	unnamed protein product	0	68	957	1058	78	11
TC009328	288	LDEC004416-PA	242	unnamed protein product	1.0E-148	82	235	420	94	1
TC006188	1258	LDEC006770-PA	247	unnamed protein product	8.0E-115	67	243	360	81	7
TC015322	518	LDEC020740-PA	517	unnamed protein product	0	94	517	899	97	0
TC011725	256	LDEC007421-PA	244	unnamed protein product	9.0E-124	74	238	355	82	5
TC014785	756	LDEC005485-PA	801	unnamed protein product	0	82	618	993	88	3
TC014109	173	LDEC016281-PA	173	unnamed protein product	2.0E-123	97	173	348	100	0
TC015727	710	LDEC005185-PA	521	unnamed protein product	0	92	418	793	95	1
TC015014	1684	LDEC017401-PA	1680	unnamed protein product	0	96	1686	3137	97	1
TC014300	900	LDEC003093-PA	925	unnamed protein product	0	47	949	735	65	8
TC013939	805	LDEC008911-PA	742	unnamed protein product	0	74	548	748	83	7
TC014413	425	LDEC012710-PA	425	unnamed protein product	0	85	411	701	92	0
TC014931	484	LDEC005233-PA	485	unnamed protein product	1.0E-144	48	479	427	66	3
TC015935	969	LDEC014614-PA	303	unnamed protein product	9.0E-158	78	289	469	89	0
TC014730	507	LDEC012509-PA	548	unnamed protein product	0	66	521	637	82	3
TC030619	805	LDEC010363-PA	1034	unnamed protein product	8.0E-112	60	388	367	66	21
TC012455	1206	LDEC017013-PA	660	unnamed protein product	0	64	650	721	78	9
TC011204	204	LDEC005567-PA	176	unnamed protein product	4.0E-57	61	204	181	69	14
TC011120	578	LDEC018675-PA	609	unnamed protein product	0	81	563	944	86	6
TC014294	1112	LDEC008327-PA	961	unnamed protein product	0	79	721	1125	89	4
TC013746	376	LDEC008164-PA	376	unnamed protein product	0	86	376	704	95	0
TC016270	606	LDEC000567-PA	605	unnamed protein product	0	77	592	963	86	3
TC013245	431	LDEC012456-PA	427	unnamed protein product	2.0E-179	74	440	511	83	5
TC013003	525	LDEC007222-PA	548	unnamed protein product	0	56	554	588	74	8
TC012723	534	LDEC010834-PA	227	unnamed protein product	8.0E-60	73	230	199	76	7
TC011708	312	LDEC010231-PA	374	unnamed protein product	1.0E-63	64	198	208	72	10
TC030579	360	LDEC006220-PA	376	unnamed protein product	0	88	360	677	96	0
TC030625	273	LDEC010014-PA	273	unnamed protein product	7.0E-154	83	270	434	90	3
TC030666	263	LDEC023007-PA	235	unnamed protein product	2.0E-84	73	195	255	83	0
TC015321	327	LDEC001822-PA	327	unnamed protein product	0	99	327	677	99	0
TC013571	291	LDEC019570-PA	143	unnamed protein product	7.0E-42	72	124	143	82	2
TC012381	361	LDEC021145-PA	295	unnamed protein product	4.0E-126	89	208	367	94	0
TC030708	815	LDEC018094-PA	672	unnamed protein product	6.0E-134	68	469	417	75	10
TC032227	595	LDEC003557-PA	600	unnamed protein product	0	71	595	918	86	0
TC033679	217	LDEC009011-PA	490	unnamed protein product	2.0E-62	60	221	204	66	20
TC031473	1041	LDEC005909-PA	1018	unnamed protein product	0	82	1041	1713	89	4
TC031972	2137	LDEC018190-PA	1649	unnamed protein product	0	91	1545	2858	96	0
TC031145	1173	LDEC012775-PA	392	unnamed protein product	0	95	388	686	98	0
TC033251	534	LDEC001072-PA	534	unnamed protein product	0	77	520	821	88	1

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1900

1800	Su(var)205 updated	Suppressor of variegation 205	CG8409	28F2-28F3	89	15	60
1801	Rrp42 updated	Rrp42	CG8395	52D14-52D14	4	3	18
1802	VGAT updated	Vesicular GABA Transporter	CG8394	50E4-50E4	5	5	14
1803	Prosß1 updated	Proteasome ß1 subunit	CG8392	52D13-52D14	6	7	42
1804	vlc updated	vulcan	CG8390	41F9-41F8	13	10	97
1805	Arf79F updated	ADP ribosylation factor at 79F	CG8385	80B1-80B1	21	13	218
1806	gro updated	groucho	CG8384	96F10-96F10	138	13	145
1807	ap updated	apterous	CG8376	41F-41F8	134	78	88
1808	dmt updated	dalmatian	CG8374	85E5-85E5	19	8	26
1809	cg updated	combgap	CG8367	50E1-50E1	37	23	117
1810	E(spl)m8-HLH updated	Enhancer of split m8, helix-loop-helix	CG8365	96F10-96F10	87	12	6
1811	Drep3 updated	DNA fragmentation factor-related protein 3	CG8364	48D8-48D8	3	3	7
1812	Papss updated	PAPS synthetase	CG8363	76D1-76D2	16	10	210
1813	E(spl)m7-HLH updated	Enhancer of split m7, helix-loop-helix	CG8361	96F10-96F10	34	12	13
1814	Tcp-1? updated	Tcp-1?	CG8351	85B1-85B2	12	8	66
1815	E(spl)m3-HLH updated	Enhancer of split m3, helix-loop-helix	CG8346	96F10-96F10	11	4	51
1816	RpIII128 updated	RNA polymerase III 128kD subunit	CG8344	48D8-48D8	2	2	23
1817	sfl updated	sulfateless	CG8339	65B3-65B4	24	15	31
1818	E(spl)m?-BFM updated	Enhancer of split m?, Bearded family member	CG8337	96F10-96F10	14	5	11
1819	E(spl)m?-HLH updated	Enhancer of split m?, helix-loop-helix	CG8333	96F9-96F9	19	5	11
1820	RpS15 updated	Ribosomal protein S15	CG8332	53C8-53C8	9	11	663
1821	tomboy40 updated	tomboy40	CG8330	42A14-42A14	3	3	12
1822	E(spl)m?-HLH updated	Enhancer of split m?, helix-loop-helix	CG8328	96F9-96F9	12	6	7
1823	CG8326 updated	-	CG8326	16B9-16B10	3	4	26
1824	l(2)k14710 updated	lethal (2) k14710	CG8325	42A13-42A13	10	9	36
1825	ATPCL updated	ATP citrate lyase	CG8322	52D9-52D11	14	12	76
1826	?Tub67C updated	?-Tubulin at 67C	CG8308	67C4-67C4	39	15	41
1827	CG8306 updated	-	CG8306	53C9-53C9	5	6	73
1828	CG8303 updated	-	CG8303	53C9-53C10	11	9	10
1829	Mlf updated	Myelodysplasia/myeloid leukemia factor	CG8295	52D2-52D3	24	10	131
1830	Diap2 updated	Death-associated inhibitor of apoptosis 2	CG8293	52D2-52D2	37	7	62
1831	bdg updated	bedraggled	CG8291	52D2-52D2	12	5	43
1832	ADD1 updated	ADD domain-containing protein 1	CG8290	48D5-48D5	13	10	93
1833	Rab8 updated	Rab8	CG8287	76D2-76D3	19	15	84
1834	P58IPK updated	P58IPK	CG8286	85D27-85D27	6	4	37
1835	boss updated	bride of sevenless	CG8285	96F8-96F8	58	5	31
1836	Ef1?48D updated	Elongation factor 1?48D	CG8280	48C5-48C5	21	17	2001
1837	bin3 updated	bicoid-interacting protein 3	CG8276	42A13-42A13	56	36	50
1838	Mtor updated	Megator	CG8274	48C5-48C5	15	6	37
1839	Sln updated	Silnoon	CG8271	48C4-48C5	9	4	5
1840	DCTN2-p50 updated	Dynactin 2, p50 subunit	CG8269	44F3-44F3	15	9	26
1841	Bx42 updated	Bx42	CG8264	8C9-8C9	7	4	68
1842	G?1 updated	G protein ? 1	CG8261	44F3-44F5	26	15	183
1843	Gpo-1 updated	Glycerophosphate oxidase-1	CG8256	52C8-52C8	25	18	145
1844	Pgi updated	Phosphoglucose isomerase	CG8251	44F6-44F6	23	13	253
1845	Alk updated	Anaplastic lymphoma kinase	CG8250	53C12-53C13	30	6	20
1846	Poxn updated	Pox neuro	CG8246	52C7-52C7	38	6	2
1847	CG8243 updated	-	CG8243	44F7-44F8	4	3	72
1848	pea updated	peanuts	CG8241	50E1-50E1	9	7	31
1849	Buffy updated	Buffy	CG8238	48C1-48C1	11	10	4
1850	Rcd1 updated	Reduction in Cnn dots 1	CG8233	50E1-50E1	4	4	78
1851	Tcp-1? updated	T-cp1?	CG8231	13E13-13E14	10	8	123
1852	Vps45 updated	Vacuolar protein sorting 45	CG8228	85D25-85D25	11	6	11
1853	babo updated	baboon	CG8224	44F11-44F12	46	18	96
1854	Pvr updated	PDGF- and VEGF-receptor related	CG8222	28F4-28F5	64	32	87
1855	CG8219 updated	-	CG8219	65A8-65A8	8	5	10
1856	Cep89 updated	Centrosomal protein 89kDa homolog	CG8214	52B5-52C1	3	2	4
1857	CG8213 updated	-	CG8213	44F12-45A1	11	6	17
1858	IntS2 updated	Integrator 2	CG8211	16B10-16B10	5	5	18
1859	Vha14-1 updated	Vacuolar H+ ATPase 14kD subunit 1	CG8210	52B2-52B2	8	6	33
1860	fus updated	fusilli	CG8205	52B3-52B5	38	16	93
1861	par-1 updated	par-1	CG8201	56D9-56D11	81	21	159
1862	l(1)G0136 updated	lethal (1) G0136	CG8198	13E12-13E12	4	4	5
1863	CG8197 updated	-	CG8197	45A1-45A1	2	3	12
1864	Vha36-1 updated	Vacuolar H+ ATPase 36kD subunit 1	CG8186	52A10-52A10	6	6	115
1865	Nach updated	Nach	CG8178	53C14-53C14	6	5	-
1866	dup updated	double parked	CG8171	51F11-51F11	25	12	127
1867	Ilp2 updated	Insulin-like peptide 2	CG8167	67C8-67C8	18	7	2
1868	unc-5 updated	unc-5	CG8166	51F7-51F11	26	9	42
1869	Tfb1 updated	TFB1 ortholog (S. cerevisiae)	CG8151	50F6-50F6	11	10	42
1870	Spn28F updated	Serpin 28F	CG8137	28F5-28F5	7	2	9
1871	Eip75B updated	Ecdysone-induced protein 75B	CG8127	75A10-75B6	154	66	241
1872	pasi2 updated	pasiflora 2	CG8121	85D11-85D11	7	3	35
1873	HP1e updated	Heterochromatin Protein 1e	CG8120	85D11-85D11	9	4	1
1874	mam updated	mastermind	CG8118	50C23-50D3	205	56	59
1875	CG8117 updated	-	CG8117	13E3-13E3	4	2	5
1876	pbl updated	pebble	CG8114	66A18-66A19	68	23	85
1877	syd updated	sunday driver	CG8110	66A20-66A20	11	8	168
1878	CG8108 updated	-	CG8108	67C11-67D1	12	12	172
1879	nudE updated	nudE	CG8104	67D1-67D1	10	7	58
1880	Mi-2 updated	Mi-2	CG8103	76D3-76D4	70	33	91
1881	Picot updated	Picot	CG8098	53C15-53D1	7	8	46
1882	scb updated	scab	CG8095	51E10-51E11	41	17	70
1883	row updated	relative of woc	CG8092	51E5-51E7	8	7	102
1884	Dronc updated	Death regulator Nedd2-like caspase	CG8091	67D2-67D2	78	20	75
1885	CG8086 updated	-	CG8086	28F5-29A1	9	7	23
1886	Vang updated	Van Gogh	CG8075	45A4-45A6	38	9	40
1887	Mys45A updated	Mystery 45A	CG8070	45A7-45A8	6	5	15
1888	Su(var)2-10 updated	Suppressor of variegation 2-10	CG8068	45A8-45A9	28	19	147
1889	CG8064 updated	-	CG8064	91A1-91A1	6	7	17
1890	out updated	outsiders	CG8062	18C2-18C2	22	10	39
1891	alc updated	alicorn	CG8057	45A9-45B1	15	8	59
1892	shrb updated	shrub	CG8055	45A12-45A12	16	10	66
1893	eIF-1A updated	Eukaryotic initiation factor 1A	CG8053	91A1-91A1	18	12	179
1894	Btk29A updated	Btk family kinase at 29A	CG8049	29A1-29A3	65	29	129
1895	Vha44 updated	Vacuolar H+ ATPase 44kD subunit	CG8048	53B3-53B4	19	14	128
1896	mRpL19 updated	mitochondrial ribosomal protein L19	CG8039	85A5-85A5	4	4	12
1897	CG8036 updated	-	CG8036	85A5-85A5	31	21	113
1898	VhaAC45 updated	Vacuolar H+ ATPase AC45 accessory subunit	CG8029	45B4-45B4	9	11	180
1899	eIF4E-3 updated	eukaryotic translation initiation factor 4E-3	CG8023	66C1-66C1	7	6	25

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100

target gene	phenotype
CG4027	embryonic
CG17927	embryonic
CG5178	embryonic
CG5178	embryonic
CG13538	embryonic
CG1637	embryonic
CG5186	embryonic
CG9553	embryonic
CG10504	embryonic
CG10067	embryonic
CG14216	embryonic
CG4046	embryonic
CG6721	embryonic
CG7930	embryonic
CG3083	embryonic
CG34358	embryonic
CG6058	embryonic
CG1560	embryonic
CG2708	embryonic
CG6340	embryonic
CG7178	embryonic
CG4120	embryonic
CG12338	embryonic
CG9968	embryonic
CG9432	embryonic
CG6831	embryonic
CG13922	embryonic
CG4843	embryonic
CG8667	embryonic
CG9623	embryonic
CG32019	embryonic
CG32019	embryonic
CG1915	embryonic
CG1915	embryonic
CG32019	embryonic
CG5820	early larval
CG5820	early larval
CG1804	early larval
CG4875	early larval
CG31605	early larval
CG4006	early larval
CG15319	early larval
CG18102	early larval
CG14029	early larval
CG14996	early larval
CG4589	early larval
CG3193	early larval
CG10506	early larval
CG4027	early larval
CG34109	early larval
CG1242	early larval
CG11579	early larval
CG9946	early larval
CG9946	early larval
CG4035	early larval
CG14084	early larval
CG33135	early larval
CG4016	early larval
CG8016	early larval
CG30415	early larval
CG4797	early larval
CG32528	early larval
CG4239	early larval
CG1967	early larval
CG11430	early larval
CG17117	early larval
CG4307	early larval
CG4307	early larval
CG2216	early larval
CG8960	early larval
CG12157	early larval
CG6905	early larval
CG10293	early larval
CG5268	early larval
CG8189	early larval
CG5386	early larval
CG16812	early larval
CG6223	early larval
CG6223	early larval
CG5599	early larval
CG5599	early larval
CG7610	early larval
CG6378	early larval
CG6378	early larval
CG1163	early larval
CG10811	early larval
CG10811	early larval
CG13389	early larval
CG1263	early larval
CG12750	early larval
CG10149	early larval
CG14788	early larval
CG8877	early larval
CG12101	early larval
CG12101	early larval
CG13185	early larval
CG17331	early larval
CG17331	early larval
CG17521	early larval

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>TC002601\|TC002601-RA	TC002601	TC002601-RA		>TC032227 transcript1
ATGCCGAATACAACCCTTGAGAACTCACCCAATGCGGTGCTCAACAAGTCAGTGGCTGAA	TC004420	TC004420-RA
AGGTACATGCATTTACCGTGCCCCGAAAATAAGGTAAAAGCCACCTACATATGGATTGAT	TC002933	TC002933-RA		gttttttca gttgtgaaa cactttaaa cgtgttcat
GGGACTGGTGAAAATGTCAGGGCGAAAACACGCACAGTCGATTTCGTCCCAAAGAAACCC	TC003405	TC003405-RA		ttttagaca aaaacgtga tagtaaata aaaaataca
GAAGAGTTGCCGGTTTGGAACTACGACGGCAGTTCCACATACCAAGCCGAAGGCACCAAC	TC000165	TC000165-RA		atgccgact gtgggtgtc aagcgcaat ttgctattc
TCTGACACATATCTATGTCCTGTCGCCATCTACAACGACCCCTTCAATGGGGGCAACCAC	TC000040	TC000040-RA		gaagccctt gggcgcact ttcaccgac gatgaattc
AAGTTGGTCATGTGCGACACCTACAAATACAACAAAAAACCAACCGAAACTAACCACCGG	TC004683	TC004683-RA		cagcgttta tgcttcgag ttcggtctt gaactggac
CACACGTGTCTGCAAGCCATGGAGGCGGCTAAAGACACCAAACCTTGGTTCGGTATCGAG	TC003818	TC003818-RA		gaagtcaca actgaaaaa cagatgata agtaaggaa
CAGGAGTACACTTTGCTCGACATGGATATGAGACCTTTGGGGTGGCCCAAGAATGGGTTT	TC003752	TC003752-RA	PH	caaggggag gattcagcc caggcggcg ggagcctcc
CCGGGACCCCAAGGGCCTTACTATTGCGGTGTGGGGGCTAATAAGGTCTACGCACGTGAT	TC003944	TC003944-RA		gaggaagtc atttatcga attgacatt cctgcaaac
ATTGTAGAGTCTCACTACAGTGCTTGTCTGTATGCTGGTATTAATATTGCTGGAACCAAT	TC004425	TC004425-RA		agatacgat ttattgtgt cttgaaggc atttcatta
GCTGAGGTCATGCCAGCTCAATGGGAGTATCAGGTTGGTCCCTGTGAGGGTATTTCCATC	TC001600	TC001600-RA		ggaattaaa atatttcag gggaaaatt cagccgccg
GGGGATGAATTGTGGGTCTCGAGGTATATTTTGCATCGTGTCGCCGAAGATTTTGGGGTT	TC002574	TC002574-RA		gtttacaaa cgtatcaaa ccgtcatca gacagtatt
ATTGTCACGTTTGATCCTAAGCCGATTGAAGGCGATTGGAATGGAGCGGGGGCTCATACT	TC004029	TC004029-RA		caaaaaatt cacgtcaca cccgaaacg gcgaaaatc
AACTTCTCCACTAAGGCGATGAGAGAAGATGGAGGAATTATTGAAATCGAGAAAGCCATC	TC003020	TC003020-RA		aggccttat atcgtaggc gccgttttg cgtaattta
GATAAGCTCAGCCGAAACCACCTTAGACACATCCAGGCCTACGATCCTAAGGGAGGAAAG	TC003731	TC003731-RA		tacttcact caagattct tacaacagt ttcattgat
GACAACGAACGTCGTCTCACCGGTCGCCATGAAACTTCCTCGATCCATGACTTCAGTGCA	TC000082	TC000082-RA		ttgcaagat aagttgcat cagaatatt tgccgcaaa
GGTGTGGCTAACCGTGGCGCGAGTATTCGTATTCCTCGCGGATGTGCAGAAGATAAGAAG	TC002003	TC002003-RA	CACT	cgcacgctt gtctcaatc gggacgcac gatttagat
GGATATCTTGAAGATAGGAGACCATCTTCAAATTGCGATCCGTACGCAGTATGTGAAGCT	TC000029	TC000029-RA		acagttcag gggcccttc acctatgac gctaaacca
TTGGTCCGAACATGTATTCTAGATGAATAA	TC000161	TC000161-RA		ccttctgag tttaagttt gtaccactt aatcaaacc
>TC004420\|TC004420-RA	TC002507	TC002507-RA		aaagagtgt gacggcaac ggcgttatg gagctctat
ATGTCTAAAAAACGCGGAAACAAAAAGAATTTAAATTTGGAAAGTGATAACGAGGACGAA	TC000614	TC000614-RA		tcagcgcac gcgcagcta aaacaatac ttgcacatc
GGGCTTGTTACGAAAGGAGAGGCCGAAAAAGGTAACATAACCTCAAAACCGAGTAAGAGT	TC004760	TC004760-RA		atcaaagac agccctgta tatccactc gttttggac
AAAGCCCCCAAAAAGGGTAAAAAGGGCAAAAAAGACGACTGGAGCGATGATGACGATGAT	TC003079	TC003079-RA		agtaatggg gttatttta tcccttccg ccgattatt
AAAACGGTCTCTCTGATTGATAACGTGGACGAGGAGATTCAACCGGTGGCGAAAAAGAGT	TC000258	TC000258-RA		aatggggat cactccaaa attacactc aacaccaaa
GCAAAGAAGAAGTCGAAAAAGAAGGAACATGAGTCCGGTAGTGAAGATGAAGAAGATAAA	TC000801	TC000801-RA		aatgttttg attgaatgt acggcaact gatttgact
GTCGAGGTTAAGGTTGAGAATAAAAAGAAAGCTGGAAAAAAAGGTAAAGGTAAAAACGAT	TC000069	TC000069-RA		aaagcccgc attgttgtc gatactttg gtttgtatg
TGGTCGGATAATGACAGTGAAGTGGAACTGCAAATATCGGACGTTGAGGAAGAAATTCAA	TC002881	TC002881-RA		ttcagccag tattgcaaa gaacctttt actgtggaa
CCGGTGAAGAAAAGTAGCAAAAAGGTTGCTAAAACCAAAAAGAAGAAAGATCTGAGTGAG	TC004599	TC004599-RA		gcttgtgag gtgattacg gctgatggt gaatccata
GAAGATGAAATCCTTGAGGAACCAGTTGAAGAGTCAGACAAAGAAGAACCTGACGAAATC	TC003747	TC003747-RA		acttacccc gacttaacg tatcgtaac gaagtgatc
GCGGAAAAAGTATCAGAACTGCAAATAACTGAAGCTAAGAAGGAACCAGAAGAGAAGAAA	TC007891	TC007891-RA	GLEAN_07891	tcagccgat aaagccaat gctgtgata ggcatcagt
CTCACCCACAAGGAGAAGAAAAAGCTGAAGAAGCAGCAAGAATACGAGAAACAAATGGAA	TC006902	TC006902-RA		gagtcaccg gaaagtatt acaaagctt ttaaataaa
ACCCTCCTTAAAAAAGGTGGCCAAGGTCACTCAGACCTTGACAGTAACTTCACAGTCTCC	TC007846	TC007846-RA	GLEAN_07846	atgtgtttg aagtcggaa ctgacttct gacggaagc
CAGTCGCAAAAAACCGCCGGACAATTGGCCCAATTAGAAAATGCCGTTGATATTAAAATC	TC004949	TC004949-RA		agtataaaa gtaacaatc ccacccaca agacatgac
GAAAATTTCAGTATCTCGGCTAAAGGCAACGATTTATTCGTAAACGCGAATTTGTTAATC	TC010405	TC010405-RA	SRP	attatccac ccttgcgac atctacgag gacgtggct
GCCAACGGGCGTCATTACGGTCTTGTGGGGCCCAATGGTCACGGTAAAACAACACTTTTG	TC011058	TC011058-RA		atagctttc ggttataat aaaatcgtt cgcacttta
CGTCATATTGCGCAACGGGCTTTCGCGATACCCCCAAATATCGATATTTTGTATTGTGAA	TC009040	TC009040-RA		cccaaaaca aacacaatc ggctcccaa aaccccatt
CAAGAAGTGGTCGCTGATGATTTTTCAGCGGTTGAATCGGTGCTTAAATCGGATGTGAAA	TC006375	TC006375-RA		aacaaactg tcggatctt ttgcgagca ccgatcgcc
CGGACTGAATTGTTAGAAGAATGTAAAAAATTAGAGGATGCGTTTAATACCGGGGATTTG	TC010557	TC010557-RA		caagctggt ttcaccgaa gctttgacc ttttctctg
GGCGTTCAGGACCGGCTTAATGAAGTTTATGCCGAATTGAAGGCCATTGGGGCGGATTCG	TC009010	TC009010-RA		tgttcccga gacgacatt tcaaccaaa cttggccta
GCCGAACCTAAGGCGAGGAGAATCTTAGCTGGTCTAGGATTCACTAAAGAAATGCAAGAT	TC006982	TC006982-RA		aaatcagtg gacgaagtc ccggctgtg cacatttca
AGAGCAACTAAAAATTTTTCTGGTGGATGGAGAATGAGAGTGTCACTAGCCAGAGCGTTG	TC011082	TC011082-RA		aatccgaaa actctcgaa tttcaagtg tgccgcact
TATATAGAACCCACTTTATTACTTCTTGATGAACCAACGAATCATTTAGATTTGAATGCA	TC005869	TC005869-RA		actttaatt cccgggatt ttgaaaaca atcgcagcc
GTTATTTGGTTGGATAATTATTTGCAAGGGTGGAAAAAAACTCTACTTATCGTTTCACAC	TC008263	TC008263-RA	GLEAN_08263	aataaaaaa atgccgctg ccgcttaaa attttcgaa
GACCAGTCATTCTTAGATAATGTTTGTAATGAAATTATCCATTTAGATAATCAAAAGTTG	TC006281	TC006281-RA		gtctcggac gtcgtcatc aaggaccca tccacagaa
TATTATTACAAAGGGAATTACTCAATGTTTAAAAAAATGTACCAACAAAAACGCAAAGAA	TC007640	TC007640-RA	GLEAN_07640	gtcggggcg agaaacgag cgccggatt tgtgcagtg
ATGATTAAAGAATACGAGAAGCAGGAAAAACGTTTGAAAGAGTTAAAGGCACACGGATCG	TC009491	TC009491-RA		aattgcaac aaaaacgcc ggttttgaa gtggtccac
TCGAAAAAACAAGCCGAAAAGAAACAAAAAGAGGCTTTGACGCGAAAACAGGAGAAGAAC	TC006253	TC006253-RA		ggcctttta gacaagatt atgatgctg ttggaggtg
AGAACGAAAATGCAGAAACAAGAGGACGAAACAGCCCCAACTGAACTTCTACAAAAACCG	TC008407	TC008407-RA	GLEAN_08407	ccctggaac ccgaataag acccccaaa gggtattat
AAAGAATATTTCGTCAAATTTTCATTTCCGGAACCTCCGCCTCTACAACCCCCAATTTTG	TC008190	TC008190-RA	GLEAN_08190	ctgcaagcg tgtgaagat tcggctttt tttccaggc
GGGCTTCATAACGTAACTTTTGCATATTCGGGCCAAAAACCCCTCTTCCGAAACACCGAC	TC008671	TC008671-RA		aggtgtgcc aaggtgatt tgtgacggg agcgaaatt
TTCGGTATCGATATGAGCAGCAGAGTGGCAATAGTTGGTCCGAACGGAGTCGGAAAATCC	TC008662	TC008662-RA		gggaaaatc ggggttttg cacccgaat gttttgcat
ACATTTTTGAAATTATTAACCGGTGATTTGGACCCGCAACAAGGGGAAGTCCGGAAAAAT	TC006047	TC006047-RA		aaatttgag ctaactaat ccttgctcg tgtgtcgag
CATCGTTTGAGGATTGGTCGTTTTGATCAACATTCAGGTGAGCATTTAACGGCCGAAGAA	TC010367	TC010367-RA		attaatatc gagccgttt gtgtaggga taaggaata
ACACCCGCTGAATATCTGATGCGATTGTTTGATCTGCCGTACGAAAAATCCCGAAAGCAA	TC009191	TC009191-RA		aatggaaat tgaaattaa ctgactttt tttaccctt
TTGGGGACTTTTGGTCTAGCGAGTCATGCTCACACTATCAAAATGAAGGACTTGTCCGGG	TC006679	TC006679-RA		tccaccaaa ccatgtttt aatcaaata aaacatttc
GGACAGAAAGCACGAGTGGCTTTAGCCGAATTGTGTCTTAACGCACCGGATGTTCTCATT	TC007999	TC007999-RA	GLEAN_07999	taacgtc
TTGGATGAACCGACGAATAATTTAGATATTGAATCGATTGATGCACTAGCTGAGGCCATT	TC005313	TC005313-RA
AACGACTTCAGTGGAGGGGTTATTATAGTGAGCCACGACGAACGACTTATACGTGAAACT	TC006514	TC006514-RA		>TC033679 transcript1
GATTGCGCCTTGTACGTAATAGAAGACCAGACCATAAACGAATTAGACGGCGACTTCGAC	TC007510	TC007510-RA	GLEAN_07510
GACTACCGCAAAGAGCTCTTGGAGAGTCTGGGTGAAGTCATCAACAGCCCAAGTATTGCA	TC011068	TC011068-RA		aatttgaga ggtcctaaa ccatagttt tatttccac
GCAAACGCTGCCATTGCTCAATAA	TC009328	TC009328-RA		tgtaatata cgcacacgg gacgatctc ttcccgttt
>TC002933\|TC002933-RA	TC006188	TC006188-RA		tagcaatta gtgcatttc cttttattt ttatttttt
ATGACACAGTTTCTGCCACCGAACTTGCTCGCTTTATTCGCACCACGCGACCCCATTCCG	TC015322	TC015322-RA	GLEAN_15322	tagaatttt tgcttattt tgtttttgt ttttttttc
TACCTGCCTCCGGTAGCAAAGCTACCCCATGAGAAGAAATCGAGGGGGTATCTGGGCGTT	TC011725	TC011725-RA		tcctttcac gtgtcccct accgcacta acttgtttt
GGGGCGTTCCTCAAGGAGTTCGAGGACCCCAAAGACACTCCACCACCGACCAGGGTGGAA	TC014785	TC014785-RA		ctgttactt acttccttt tcctcgtcc tgaaattcc
ACAAGGGAGGAGCGCATTGAGAGACGACGAAGGGAACGAGCGGAACAAGTTGCGTATAAA	TC014109	TC014109-RA		tcacacagc caaaggacg cacgaacat agagctgcg
TTGGAGCAAGAGATCGCAGTCTGGGACCCCAATTCGGCCCCGAATATCACAGTGGACCCC	TC015727	TC015727-RA	GLEAN_15727	tgaacaatt catcctagc cgacggcgt atcgcaaac
TTCAAAACGCTTTTTGTAGCTAGAATTAATTATGACACGTCGGAGTCGAAGTTGAGAAGA	TC015014	TC015014-RA	GLEAN_15014	tatgaccgc gttcaagcc caaaacatc ggcctccag
GAATTCGAAGTGTATGGTCCGATCAAGAAGATTGTCTTGATTCACAATAGCGTCAATGGG	TC014300	TC014300-RA		tcccgcctc tggctcctc tgcatcatc actccgcac
AAACCAAGGGGGTATGCTTTCATAGAATATGAACATGAAAGAGATATGCACTCTGCATAC	TC013939	TC013939-RA		tcctcaagg gccaatcac taaggtatt gcacaagag
AAACATGCTGACGGAAAGAAAATTGACGGAAGACGGGTTTTAGTTGATGTGGAGAGAGCC	TC014413	TC014413-RA		caccctctt tgatccgga aaaagcatc gaaaatact
CGTACCGTCAAGGGTTGGTTACCTCGGCGTTTAGGTGGTGGTCTTGGCGGGACCCGAAGA	TC014931	TC014931-RA	GLEAN_14931	atccttgtc ctcgatccc agtcggttg tggagtatt
GGAGGTCCAGAGGTAAATATCAAACATTCAGGTCGCGAGGACAACGAGAGGGAGAGGGAA	TC015935	TC015935-RA		gttttcagt gcttttttc gagttgctc tatgtcttg
AGGTACAGGTTAGAGCGCGAACGCGAAGAGAGGGGTGGTGGTAGGGAACGTGAAAGGGAG	TC014730	TC014730-RA		gtaatggta cgcttgtat acgtagtac agtagttgg
CGCGATAGGGAAAGGGAACGTGGGGTGGCGTACGAAAGAAGACGCTCTAGGTCAAGGGAA	TC030619	TC030619-RA		ccaccagag ggtaaaggt aagtcggac ctcaggaga
CGAAGAAGAAGAAGTCGCTCACGTTCGCCAAGACGAGAGAAAAGAAGACGCAGCAAGGAG	TC012455	TC012455-RA		tgaattttg tgaacgcga caacaacaa gggccgaag
CGCGTTAGGGAAGAATTTGAGGAAACCTTTGACCGGCGGTCACGTGAGAAGGACAGGGGA	TC011204	TC011204-RA		cataaaaca aaatcgcct cacgttcat tcagcactc
GATAGGGAACGTGACCGGGAAAGAGACCGCAAACGCAGACGTTCAAAATCCAGGGACAAA	TC011120	TC011120-RA	ROP	gatgcttct tttttctgt tcgcaccat ctaaacgcg
GACCGCGAACGCAAACGTGAGCGGCGAGAAAGACGTGAGCGAGAACGCGGTGAAAGACTT	TC014294	TC014294-RA		acgatcact attggatta tttcggaca cgctgtata
GAATACATCAAAACTGATGATGGAGGGGAAGTCCGAATCAAAGAAGAACCCATTGATGAT	TC013746	TC013746-RA		tttctgaat gttggcatg tgctattgt ttagctcac
TATCCAGAATACCCGCAATACCCTGCAGAAGCTTATGATCAGACTCGAGTCAAATATGAA	TC016270	TC016270-RA		gaacacttg gcggagttg atgcccata ttcgagcag
GACGAGGATGAACAAAAATACGAACCAGACAATACAAACGGCAGTCGTCAGTATGACGAC	TC013245	TC013245-RA	FKH	ctgagggcc aaaggagaa gtgggcaat gcgtaccct
GAATATGAGGAGGGAGAAGCTTATTAA	TC013003	TC013003-RA		ttgcatgtc ggttctact gctggaccc accttacac
>TC003405\|TC003405-RA	TC012723	TC012723-RA		tgggctcct ctcaatatc aacaacact tgtcactgg
ATGGGCCATCACGTGAACGGCTTAGAAATGGAAAAGAAGAATCCCAACGAAGAAGAGCCA	TC011708	TC011708-RA		gtaataata cacacagac actttgtgc atgtgcatg
CCGCAAAGTGTGGAAAGTGTGGAATTGCTGCTTTTTCCACTAATTGGCGCAAATGTTGTA	TC030579	TC030579-RA		gtgtgtacg tctcttctc tcgtttttt ttgcaaaat
AATAATCCATTGTTACCAGTTTATGTCCAAAAACGTGCCTCACCTGATTGGCATGCCATC	TC030625	TC030625-RA		catcattta tcgttaaat cgagtcgag tttcaatcg
ATGTGTAAAGATTACCAAGTAGTCTTATCGGTTCGGTTCGTTGTCTTCCTGTTCAGTGAA	TC030666	TC030666-RA	GLEAN_15729-OG20814	taccgtttt tcttgtttt tataccagt cgctgttat
ACTGATAAAAGTGACAACGAGCGTTCGGTCCCAACATTTCCCTCGAAAAACAACCGGCGG	TC015321	TC015321-RA	GLEAN_15321	cgggccgga aaaagacca ccacaaact tttgtacct
AAAGTTAAAAACTGTGCTGTGCTCGTGTACGTGTCGGAGTTCCGCTATCGGCAAACACAA	TC013571	TC013571-RA		atcgcaagt accgatggt aggtatacc gcaggtaag
ACCTATAATGAACGTTTGATTATGATTTGTATTTTCAAATCATTCCCCGATCGTTTAACG	TC012381	TC012381-RA		acgaataaa tcgctcatt acttttggt ctttctttc
ATACTTTCGTCCCGAAAACGGAAGCGGCTCAACAACGTGACGAATGGGACCAGCAACAAC	TC030708	TC030708-RA		caaaatttc taaaaccgg cccaatttt tactaagat
ACCAGATATACGGTCGTTTTCGACCAAGAGAACCTCAACAACACCGAAAAGAAAAAAACA				cattttaac gttaccgga tgaggtaag acaggaaac
GGATGGTTCGGCACGCGCCACTTTGTGACCTTCATGCTGTTCCTCGGAATGGCAAACGCC				tgtaagtag cgttttgtt atgcaatca aggatcttc
TATGTAATGAGGACCAACATGTCTATGGCCATCGTGGCAATGGTGAACCACACGGCAATC				aatttacat tttttaatc acacacttg ttaacgtag
GAAGCCTCACATTCGAACCACGACGAGCCGGTTGACACCGAATGCGGCGTGGATCTGCCC				cgtcttgtc actgttatc taacacgaa gatcctttt
CAGGCGAACAAATCGCACCAGGAAAACGACGGCGAATTTGTCTGGGAGACGGACATCCAG				tttgtgggt gcacgactc gtatcaatt gttggccct
GGCTACGTCCTCAGCTCCTTCTTCTACGGCTACGTCGTCACCCAGATCCCCTTCGGCATC				taccaacaa ctggtactc ttccactca cccatcctt
CTCTCCAAGCGCTACGGCAACATCTACTTCCTGGGCGTTGGCATGCTGATCAACTCCCTG				actaaaaat tactgttta ggtgcgaga gcgttcagc

↑ Previous 1 2 3 4 5 6 7 8 9 … 30 31 Next ↓

Top 40 RNAi target genes
Symbol	iB	Tc gene	Dm gene	Dm gene name
control	iB_05139	TC011976	CG3331	ebony
L2	iB_00004	TC000040	CG42341	Pka-R1
L3	iB_00011	TC000069	CG4097	Prosβ6
L5	iB_00029	TC000161	CG6202	Surf4
L7	iB_00053	TC000258	CG4904	Prosα6
L9	iB_00141	TC000614	CG18495	Prosα1
L10	iB_00322	TC002003	CG5848	cact
L11	iB_00404	TC002574	CG4659	Srp54k
L14	iB_00472	TC002933	CG8749	snRNP-U1-70K
L17	iB_00606	TC003747	CG2063	-
L25	iB_00950	TC005869	CG18174	Rpn11
L27	iB_01026	TC006281	CG17332	VhaSFD
L32	iB_01280	TC007891	CG4157	Rpn12
L37	iB_01493	TC009191	CG1250	Sec23
L39	iB_01562	TC009491	CG2910	nito
L42	iB_01709	TC010557	CG9539	Sec61α
L43	iB_01800	TC011082	CG2674	Sam-S
L44	iB_01807	TC011120	CG15811	Rop
L47	iB_02161	TC013571	CG6625	alpha snap
L50	iB_01793	TC011058	CG18102	shi
L52	iB_01857	TC031473	CG1782	Uba1
L54	iB_02377	TC015014	CG9012	Chc
L55	iB_02456	TC015321	CG6593	pp1alpha-96a
L56	iB_02457	TC015322	CG11154	ATPsyn-β
L58	iB_02531	TC015935	CG13281	Cas
L61	iB_02601	TC030625	CG12323	Prosβ5
L62	iB_02611	TC030666	CG11522	RpL6
L63	iB_02644	TC000801	CG2503	atms
L64	iB_02646	TC030619	CG8118	mam
L67	iB_02771	TC008263	CG10228	inr-a
L76	iB_03754	TC004425	CG4147	hsc70-3
L79	iB_04099	TC006253	CG8566	unc-104
L80	iB_04125	TC006375	CG5378	Rpn7
L82	iB_04192	TC006679	CG31992	gw
L84	iB_04411	TC007999	CG16916	Rpt3
L88	iB_05303	TC012723	CG12104	-
L90	iB_05404	TC013245	CG10002	fkh
L93	iB_05604	TC014294	CG1828	dre4
L94	iB_05628	TC014413	CG7269	Hel25E
L95	iB_05683	TC014730	CG12245	gcm
L100	iB_06050	TC030708	CG2252	fs(1)h

Injection of non-overlapping dsRNA fragments						The lethality of the top 40 RNAi target genes was confirmed by repeating the experiment using non-overlapping dsRNA fragments with a total dsRNA concentration of 1 µg/µl. DsRNA injections were done into 10 Tribolium larvae, respectively, and the survival animals were counted every second day. Tc-ebony was used as negative control.
Tc-ebony	d2	d4	d6	d8	d10
1000ng/µl	10	10	9	9	9
L2	d2	d4	d6	d8	d10
L2_2 1000ng/µl	6	2	2	0	0
L3	d2	d4	d6	d8	d10
L3_2 1000ng/µl	9	4	0	0	0
L5	d2	d4	d6	d8	d10
L5_2 1000ng/µl	8	0	0	0	0
L7	d2	d4	d6	d8	d10
L7_2 1000ng/µl	9	6	0	0	0
L9	d2	d4	d6	d8	d10
L9_2 1000ng/µl	7	6	0	0	0
L10	d2	d4	d6	d8	d10
L10_2 1000ng/µl	6	0	0	0	0
L11	d2	d4	d6	d8	d10
L11_2 1000ng/µl	10	1	0	0	0
L14	d2	d4	d6	d8	d10
L14_2 1000ng/µl	6	5	3	0	0
L17	d2	d4	d6	d8	d10
L17_2 1000ng/µl	7	3	2	0	0
L25	d2	d4	d6	d8	d10
L25_2 1000ng/µl	8	5	0	0	0
L27	d2	d4	d6	d8	d10
L27_2 1000ng/µl	10	5	0	0	0
L30	d2	d4	d6	d8	d10
L30_2 1000ng/µl	7	4	2	0	0
L32	d2	d4	d6	d8	d10
L32_2 1000ng/µl	7	4	4	0	0
L37	d2	d4	d6	d8	d10
L37_2 1000ng/µl	9	6	1	0	0
L39	d2	d4	d6	d8	d10
L39_2 1000ng/µl	10	4	2	0	0
L42	d2	d4	d6	d8	d10
L42_2 1000ng/µl	7	4	1	0	0
L43	d2	d4	d6	d8	d10
L43_2 1000ng/µl	10	7	2	0	0
L44	d2	d4	d6	d8	d10
L44_2 1000ng/µl	7	1	0	0	0
L47	d2	d4	d6	d8	d10
L47_2 1000ng/µl	10	2	0	0	0
L50	d2	d4	d6	d8	d10
L50_2 1000ng/µl	10	2	0	0	0
L52	d2	d4	d6	d8	d10
L52_2 1000ng/µl	8	4	0	0	0
L54	d2	d4	d6	d8	d10
L54_2 1000ng/µl	9	3	0	0	0
L55	d2	d4	d6	d8	d10
L55_2 1000ng/µl	10	4	0	0	0
L56	d2	d4	d6	d8	d10
L56_2 1000ng/µl	10	3	0	0	0
L58	d2	d4	d6	d8	d10
L58_2 1000ng/µl	10	6	5	0	0
L61	d2	d4	d6	d8	d10
L61_2 1000ng/µl	10	3	0	0	0
L61_3 1000ng/µl	9	2	0	0	0
L62	d2	d4	d6	d8	d10
L62_2 1000ng/µl	9	3	1	0	0
L62_3 1000ng/µl	10	3	0	0	0
L63	d2	d4	d6	d8	d10
L63_2 1000ng/µl	10	9	5	0	0
L64	d2	d4	d6	d8	d10
L64_2 1000ng/µl	10	9	8	0	0
L67	d2	d4	d6	d8	d10
L67_2 1000ng/µl	8	0	0	0	0
L76	d2	d4	d6	d8	d10
L76_2 1000ng/µl	10	5	0	0	0
L79	d2	d4	d6	d8	d10
L79_2 1000ng/µl	10	2	0	0	0
L80	d2	d4	d6	d8	d10
L80_2 1000ng/µl	10	0	0	0	0
L82	d2	d4	d6	d8	d10
L82_2 1000ng/µl	10	1	0	0	0
L84	d2	d4	d6	d8	d10
L84_2 1000ng/µl	10	1	0	0	0
L88	d2	d4	d6	d8	d10
L88_2 1000ng/µl	10	9	5	2	0
L90	d2	d4	d6	d8	d10
L90_2 1000ng/µl	10	6	1	0	0
L90_3 1000ng/µl	10	7	0	0	0
L93	d2	d4	d6	d8	d10
L93_2 1000ng/µl	7	1	0	0	0
L94	d2	d4	d6	d8	d10
L94_2 1000ng/µl	10	1	0	0	0
L95	d2	d4	d6	d8	d10
L95_2 1000ng/µl	10	0	0	0	0
L100	d2	d4	d6	d8	d10
L100_2 1000ng/µl	10	5	0	0	0

100

Single and double RNAi treatments with a total dsRNA concentration of 0,5 ng/µl						Single and double RNAi treatments were performed in 10 Tribolium larvae, respectively, and the number of surviving animals at different days post injection was documented. For every target gene, 10 different pairwise combinations were injected with a total dsRNA concentration of 0,5ng/µl and compared to the single injections (0,5ng/ul total concentration).
	d2	d4	d6	d8	d10
L11	9	9	7	7	5
L11+10	10	8	8	6	2
L11+44	10	10	9	8	4
L11+47	10	8	8	6	3
L11+50	10	9	5	2	2
L11+55	10	10	10	9	8
L11+67	10	7	5	4	2
L11+76	10	10	10	9	2
L11+80	10	9	8	7	5
L11+82	10	10	9	4	3
L11+84	10	10	10	7	2
L50	10	9	9	7	5
L50+10	10	8	6	5	5
L50+44	10	10	10	10	3
L50+47	10	8	5	2	0
L50+55	8	7	7	4	3
L50+67	10	9	8	6	3
L50+76	10	10	7	5	3
L50+80	9	9	9	7	5
L50+82	10	10	6	6	4
L50+84	8	8	7	5	3
L67	10	8	6	4	0
L67+10	10	10	5	5	4
L67+44	10	9	9	9	4
L67+47	10	8	7	3	1
L67+55	10	9	5	4	3
L67+76	10	6	5	3	1
L67+80	9	9	9	9	7
L67+82	10	8	6	2	0
L67+84	10	8	7	5	3
L76	10	9	5	1	0
L76+10	9	8	8	5	3
L76+44	10	5	5	4	4
L76+47	9	6	5	3	0
L76+55	10	9	7	7	4
L76+80	10	9	8	5	3
L76+82	10	9	9	6	3
L76+84	10	10	10	6	4
L84	10	9	6	3	1
L84+10	10	10	10	7	7
L84+44	10	9	9	8	3
L84+47	10	5	5	3	0
L84+55	10	10	10	9	7
L84+80	9	7	7	7	3
L84+82	10	7	7	3	2
L55	10	10	10	10	8
L55+10	10	10	9	6	7
L55+44	9	8	8	3	2
L55+47	10	10	6	4	1
L55+80	10	10	10	9	8
L55+82	9	9	9	4	1
L80	9	6	5	2	1
L80+10	10	8	8	7	6
L80+44	9	8	8	6	2
L80+47	10	10	9	7	1
L80+82	10	9	8	7	2
L82	10	8	7	2	0
L82+10	10	8	7	5	3
L82+44	10	9	9	5	2
L82+47	10	7	7	2	0
L44	9	8	8	7	0
L44+10	10	8	8	6	4
L44+47	10	8	6	3	0
L47	10	6	5	3	1
L47+10	10	4	4	2	1
L10	10	5	2	2	0
Ebony	10	9	9	9	9

↑ Previous 1 2 Next ↓

Gene sequences of the orthologous RNAi target genes published by Baum et al., 2007.
TC013867/copi coatomer	ATGCCCCTCCGTCTGGACATCAAACGCAAACTTACGGCGCGTTCCGACCGTGTAAAATGCGTCGACTTGCACCCGACCGAGCCCTGGATGCTCTGCTCGCTATACAGCGGCAATATAAACGTCTGGAATCACGAAAATCAACAACTAGTCAAAACCTTTGAAGTTTGTGATTTACCAGTACGTGCCGCAAAATTCGTACCCCGCAAGAACTGGGTGATTGCCGGCTCGGACGACATGCAAATTCGTGTTTTTAACTATAATACACTGGATCGTGTACATGCTTTTGAGGCCCATTCGGATTATGTGCGGTGTATTGTGATCCACCCCACACAGCCTTACATCCTCACAGGGAGCGATGACATGCTTATCAAATTATGGAACTGGGAGAAAGCCTGGGCCTGTCAACAAGTCTTCGAAGGCCACTCTCACTACGTAATGCAAATCGCAATCAACCCCAAAGACAACAACACGTTCGTAAGCGCGTCCCTCGACCGCACATTGAAAGTGTGGCAACTGGGTGCTTCCACCCCCAATTTCACGCTCGAAGGCCACGAGAAGGGGGTCAATTGCGTCGATTATTACCACGGGGGCGACAAACCCTACATCATTTCAGGCGCCGACGACCGTCTTGTCAAAATCTGGGACTACCAGAACAAAACATGCGTCCAAACCCTCGAAGGCCACACTCAAAACATCAGCTCGGTGTGTTTCCACCCTGAACTCCCAATCGTCCTGACAGGGAGCGAAGACGGCACTGTCAAAGTCTGGCACGCTAACACACACCGTCTTGAAAGTAGCCTCAACTACGGCTTCGAACGCGTTTGGACGATTTGCTGCCTCAAAGGCTCAAACAACGTAGTTTTCGGGTATGATGAGGGCAGTATTTTGGTCAAAATCGGGCGAGAGGAGCCGGCAGTTAGCATGGACGCCACTGGGGGCAAAATAATCTGGGCCAGACATTCGGAGCTGCAGCAAGCCAATCTGAAGGCTTTGCCCGAGGGGGCCGAGGTCAGAGACGGGGAGCGGCTCCCAGTGGCTGTGAAAGACATGGGGGCCTGCGAGATCTACCCCCAGACGATCCAACACAACCCCAACGGCCGGTTTGTTGTTGTGTGCGGCGATGGGGAGTATATTATTTACACGGCGATGGCGTTGCGGAACAAGGCCTTTGGGGCGGCTCAGGAGTTCGTTTGGGCGCAAGATTCGAGCGAATATGCGATTAGGGAAGCGGGGTCTACGGTCCGTATTTATAAAAACTTCAAAGAGAAGAAGAATTTTAAACCGGATTTTGGGGCCGAAGGGATTTTCGGGGGGTGGTTACTTGGGGTTAAGTCAGTGGCGGGGTTGACGTTCTACGATTGGGATAGTTTGGATTTAATCCGAAGGATTGAAATCCAGCCAAGGGCGATCTACTGGTCCGATAACGGCAAATTGGTGTGTCTTGCGACCGAAGATAGTTATTATATCTTATCGTACGATTCGGACCAAGTCCAGAAGGCTAAGGACGAGGGACAGGTGGCTGAGGACGGGGTTGAGTCAGCGTTTGAGGTCCTGGGGGAAGTGAACGAGACAGTTCGGACGGGGTTGTGGGTCGGCGATTGTTTCATTTACACGAATGCCGTCAACCGAATTAATTATTTCGTTGGGGGTGAGCTTGTAACCATAGCTCACTTGGACCGGCCTTTGTACGTCCTCGGCTATGTCCCGCGTGACGATCGGCTCTACCTCGCTGATAAGGAGTTAGGGGTTGTCAGTTATCAGTTATTATTGTCGGTACTCGAGTATCAAACTGCAGTAATGCGTCGTGACTTTACCACAGCCGATAGAGTATTACCCTCGATTCCGAAGGAACACCGGACTCGAGTGGCCCACTTTTTGGAAAAACAAGGCTTCAAAAAACAGGCCCTTGCTGTGAGCACGGACCCCGAACACAAATTCGAACTAGCCTTAGCCTTGGAGGACTTAAACACCGCTCGAACTCTGGCCCAAGAAGCGAACAATCCGCAAAAGTGGAGCCAATTGGGTGAATTAGCCGCTTCGACTAACAACCTCCAACTAGCCAAGGAGTGCATGCAAAGGGCGCAGGACTATGGGGGCCTCCTTCTCCTGGCTACGAGTTCCGGTGACGAAAAACTTGTGAAAACACTGGGCGAAAATACACACTCTGAAGGCAAACACAACTTGGCTTTCTTGTCGTTTTTCCTTTTGGGAGATTTGGACAAGTGTCTGGAGATTTTGATTTCGACGGGGCGTTTGCCCGAAGCCGCGTTTTTCGCTAGGTCGTACTTGCCCGATAAGATATCCGAAGTTGTGTCCTTGTGGAAGGCGAAGTTGTCGACGACGAATGAAAAGGCGGGGCAGAGTTTAGCCGATCCGAAGGATTACGAAAATTTGTTCCCGGGTTTGAATGATGCGATTGCTGCTCAACATTTTTATAGTATGGGGAGGAAAGGGTTACCGTTGGCCAAAGATGCGAAGAAAATTACGCCGAATCATGAGAGAAATGTTGTGCAAGAGATGAAGGCGCAAGGGGGCGAAGGGTTCAGTGTGCCAGTGGCGCAGACTAGCCAACCGGTTCAGAGTGAAATGAAAGCGCCGCCCAGATTGCAGCAAGAGGATGAAGATGATCTTGATCTGGATTTGGAGGGAGTTAACATTGATGATAATATAGACACCACGGATATCAATATTGATGATGATTTGTTAAGTGATTAA
TC013357/vATPase d	ATGAAGGGCTGCTTGTTCAACATCGACGCCGGTTACTTGGAGGGATTATGTCGGGGCTTCAAGTGCGGTATTTTGAAGCAATCCGATTACCTGAATTTGGTTCAGTGTGAAACCCTGGAAGATCTCAAACTGCACTTGCAAGGGACGGATTACGGGTCTTTTCTTGCCAACGAACCCTCCCCATTGGCCGTTTCGACCATTGATAATAAATTGAGGGAGAAGTTGGTCATAGAGTTCCAACATATGAGGAATCAGGCGGTTGAGCCCCTGTCTACGTTTTTGGATTTTATCACTTACAGTTACATGATTGATAATATTATTTTACTGATTACGGGGACGTTGCACCAGCGCCCCATTGGGGAGCTGATCCCGAAATGCCACCCCTTGGGGAGCTTTGAGCAGATGGAGGCTATTCATGTGGCCTCCACGCCCGCCGAGTTGTACAATGCTGTGCTCGTGGACACTCCACTGGCCCCCTTCTTCGTTGATTGTATCAGCGAGCAGGACTTAGACGAGATGAATATTGAGATTATACGTAACACTTTGTATAAGGCGTATTTGGAGGCGTTCTATGCCTTCTGTAAGGAAATCGGAGGGACTACGGCCGACTGCATGTGCGAAATTTTGGCGTTTGAGGCCGACCGTCGTGCGATTATAATCACAATCAATTCCTTTGGCACCGAATTGAGTAAAGACGATCGTGCGAAATTGTACCCACGATGTGGGAAACTCAACCCTGATGGGTTGGCCGCCCTGGTACGTGCGGAAGATTACGACCAGGTCAAAGCCGTGGCCGAGTATTATGCCGAGTATTCGAAACTTTTTGAAGGGGCGGGAAGTAATCCCGGGGATAAAACTTTGGAGGATAAGTTTTTCGAACACGAGGTGCGTTTGAACGTCCACGCGTTCTTACAACAGTTTCATTTCGGAGTTTTCTACTCCTACTTGAAACTGAAGGAGCAGGAATGTCGCAATATCGTATGGATTGCTGAATGTGTGGCGCAAAAACATCGAGCCAAGATTGATAATTACATACCGATTTTCTAA
TC008354/vATPase a	ATGACCTCTCTACCGAAGATGGGTGATGAAGAGCGCGAGAACAAATTCGGATACGTGTTCGCGGTATCCGGTCCTGTCGTTACGGCCGAGAAAATGAGCGGAGCGGCTATGTACGAGCTGGTGCGTGTGGGGTACTCCGAACTGGTCGGGGAAATTATTCGTCTGGAGGGCGAAATGGCCACTATCCAGGTATACGAAGAAACTTCAGGTGTTACGGTGGGTGATCCAGTCTTACGAACTGGTAAACCCTTGTCGGTGGAGCTGGGCCCAGGTATTATGGGTTCGATTTTTGACGGTATCCAGAGACCGCTGAAGGACATCAACGAGCTCACGCAAAGTATTTACATTCCTAAGGGTGTTAATGTGCCATCGTTGTCGCGTACGACTAAGTGGGAGTTTGCCCCATTGAATATCAAGTTGGGGTCACATCTGACAGGCGGTGATATTTACGGGATCGTCCATGAAAACACTCTCGTCAAGCATAAAATGCTGCTGCCGCCCAAAGCCAAGGGGACTGTCACATACGTCGCCGATCCCGGAAATTACACAGTCGATGAAGTCGTCTTGGAGACGGAATTCGACGGCGAGAGGACCAAATACACCATGTTGCAAGTGTGGCCTGTGCGTCAGCCCCGCCCTGTCAGCGAGAAATTGCCAGCCAATCACCCCCTATTAACTGGTCAACGCGTACTCGACTCACTTTTCCCGTGCGTCCAAGGGGGTACCACCGCCATTCCCGGAGCTTTCGGTTGCGGTAAGACCGTAATCTCGCAATCTCTCTCCAAATATTCCAACTCTGACGTTATCATTTACGTCGGTTGCGGGGAGCGTGGTAACGAAATGTCTGAAGTATTGCGGGACTTCCCCGAACTGACAGTCGAAATCGAAGGCCAAACAGAGTCTATCATGAAACGTACCGCTCTTGTCGCCAACACCTCTAACATGCCTGTAGCCGCCCGTGAGGCTTCAATTTACACCGGTATTACACTGTCTGAGTATTTCCGTGATATGGGTTACAACGTGTCGATGATGGCCGATTCCACCTCGCGTTGGGCCGAAGCTTTGAGAGAAATTTCCGGTCGTTTAGCTGAAATGCCCGCCGATTCTGGGTACCCCGCGTATTTGGGGGCCCGTTTGGCTTCGTTTTACGAGCGTGCAGGGCGTGTTAAATGCTTGGGTAACCCTGATCGTGAAGGTTCCGTTTCTATTGTCGGGGCCGTATCGCCCCCTGGTGGTGATTTCTCTGATCCCGTCACCTCAGCTACCTTGGGTATCGTACAAGTGTTCTGGGGGTTGGATAAAAAACTAGCCCAACGTAAACATTTCCCTTCGATCAATTGGCTGATTTCCTACTCTAAATACACGCGCGCTTTGGACGATTTCTACGATAAAAACTTCCAAGAGTTTGTCGCGTTGCGTACTAAGGTCAAGGAGATCTTGCAAGAAGAAGAAGACTTGTCCGAAATCGTGCAACTGGTCGGTAAAGCCTCCCTAGCCGAGACCGATAAAATCACTCTTGAGATTGCCAAGTTGCTTAAGGAAGATTTCTTGCAACAGAATTCGTACTCGTCGTACGATAGGTTCTGTCCGTTCTACAAGACGGTGGGTATGTTGAAAAATATGATCGGTTTGTACGATATGTCGCGACATGCTGTTGAAAGCACCGCGCAGTCTGAAAATAAGATCACGTGGACCGTGATCAGGGATTCCATGAGCAATATTTTGTACCAGTTGAGCAGTATGAAGTTCAAGGACCCAGTTAAAGACGGCGAGGCGAAAATCAAAGCCGATTTTGACCAGTTGTACGAGGATATTCAACAAGCCTTCAGGAACTTGGAGGATTAA
TC004873/alpha tubulin	ATGCGTGAATGTATCTCAGTTCATGTCGGCCAAGCCGGAGTCCAGATCGGCAACGCCTGTTGGGAATTGTACTGTTTGGAACATGGAATCCAACCCGACGGCCAAATGCCCTCTGATAAAACTGTCGGGGGCGGTGACGACAGTTTCAACACCTTCTTCAGCGAGACCGGTGCTGGAAAGCACGTCCCGAGGGCCGTCTTCGTCGACTTGGAACCCACTGTCGTCGATGAGGTCCGCACCGGGACTTACCGCCAGTTGTTCCACCCCGAACAATTGATCACTGGCAAAGAAGACGCCGCCAATAACTACGCCAGAGGCCACTACACCATTGGCAAGGAAATCGTCGACTTGGTTTTGGACCGCATCCGTAAATTGGCCGATCAATGCACGGGGCTCCAAGGTTTCTTGATTTTCCACTCGTTCGGTGGAGGCACCGGCTCAGGGTTCACTTCCTTGTTGATGGAAAGATTGTCGGTTGATTACGGCAAAAAATCGAAATTAGAATTCGCTATTTACCCCGCACCTCAGGTTTCTACAGCCGTTGTGGAGCCGTACAACTCGATCTTGACCACTCACACCACTTTGGAGCATTCTGACTGTGCCTTCATGGTCGACAATGAGGCGATCTACGATATTTGTCGCCGAAACTTGGACATCGAACGCCCGACTTACACCAACTTGAACAGATTGATCGGCCAAATTGTCTCCTCAATCACCGCTTCGTTGCGATTCGATGGGGCTTTGAACGTTGACTTGACCGAATTCCAGACCAACTTGGTACCTTACCCACGTATCCACTTCCCTCTAGTCACCTACGCCCCAGTCATTTCCGCCGAGAAGGCCTACCATGAACAATTATCCGTTGCGGAAATCACCAACGCCTGCTTCGAGCCCGCCAACCAGATGGTCAAATGCGACCCACGTCATGGTAAATACATGGCTTGCTGCATGTTGTACCGTGGAGATGTTGTCCCCAAGGATGTCAACGCGGCTATTGCCACCATCAAGACCAAACGTACCATTCAATTCGTTGACTGGTGTCCAACTGGGTTCAAAGTTGGTATCAACTACCAACCACCCACCGTCGTGCCAGGAGGTGACTTGGCCAAGGTACAACGTGCTGTTTGCATGTTGTCCAATACCACTGCTATCGCCGAAGCTTGGGCTCGTTTGGATCATAAATTCGACTTGATGTACGCCAAACGTGCTTTCGTCCACTGGTATGTGGGTGAAGGTATGGAAGAAGGTGAATTCTCTGAAGCTCGTGAAGATTTGGCCGCTTTGGAAAAGGATTACGAAGAGGTCGGCATGGACTCCGGAGAAGGAGAAGGCGAAGGTGGCGAAGAGTATTAA
TC009589/beta tubulin	ATGAGGGAAATCGTTCATATCCAAGCCGGCCAATGCGGCAACCAGATTGGAGCCAAATTCTGGGAAATCATCTCAGACGAGCACGGCATCGACCCCACCGGCGCCTACCACGGCGACTCCGACTTGCAATTGGAGCGCATCAACGTCTACTACAATGAAGCCTCCGGTGGCAAATACGTCCCCCGTGCCATCCTCGTGGACTTGGAGCCCGGCACCATGGACTCAGTCCGTTCCGGTCCTTTCGGCCAGATTTTCCGCCCCGACAACTTCGTCTTCGGCCAGTCCGGAGCCGGAAACAACTGGGCCAAGGGCCACTACACAGAAGGCGCCGAACTAGTCGACTCAGTCTTGGACGTGGTGCGCAAAGAGGCCGAGTCCTGCGACTGCCTCCAAGGCTTCCAGTTGACACACTCGCTTGGGGGCGGCACCGGCTCCGGCATGGGCACTCTACTCATCTCCAAAATCAGGGAGGAGTATCCCGATAGGATCATGAACACGTATTCAGTAGTACCTTCACCTAAAGTTTCCGACACGGTCGTGGAACCGTACAATGCCACGTTGTCAGTCCACCAGCTTGTAGAAAACACTGATGAGACCTATTGTATCGATAACGAAGCTCTCTATGACATCTGCTTCAGAACGTTGAAACTCACAACACCGACCTACGGTGACTTGAACCATTTGGTGTCGTTGACAATGTCGGGAGTCACGACTTGTCTGCGATTCCCCGGTCAATTGAACGCAGATCTGCGCAAATTGGCGGTCAATATGGTACCATTCCCGCGTTTGCACTTCTTCATGCCTGGTTTTGCGCCCTTGACATCGAGGGGAAGTCAGCAATACCGTGCGTTGACTGTTCCCGAGCTCACGCAGCAAATGTTCGATGCTAAGAACATGATGGCGGCGTGTGACCCCAGACATGGGAGGTACTTGACAGTGGCTGCTGTTTTCCGAGGAAGGATGTCGATGAAGGAAGTTGACGAGCAAATGCTCAACATCCAGAACAAAAACAGCAGCTACTTCGTTGAGTGGATCCCCAACAATGTCAAGACGGCCGTTTGTGACATTCCCCCACGTGGTCTCAAAATGTCGGCCACTTTCATCGGCAACTCCACCGCCATCCAAGAGCTCTTCAAGCGCATCTCTGAACAGTTCACTGCTATGTTCAGACGTAAGGCTTTCTTGCATTGGTACACCGGCGAAGGTATGGACGAGATGGAATTCACTGAAGCCGAATCAAACATGAATGACTTGGTCTCCGAGTACCAGCAGTACCAGGAGGCGACCGCCGATGAAGACGCCGAATTCGACGAGGAACAAGAAGCCGAAGTTGACGAGAACTAA

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